Results 71 to 80 of about 60,516 (300)

Carnitine palmitoyltransferase 1 facilitates fatty acid oxidation in a non-cell-autonomous manner

Cell Reports
Summary: Mitochondrial fatty acid oxidation is facilitated by the combined activities of carnitine palmitoyltransferase 1 (Cpt1) and Cpt2, which generate and utilize acylcarnitines, respectively.
Joseph Choi, Danielle M. Smith, Susanna Scafidi, Ryan C. Riddle, Michael J. Wolfgang   +4 more
doaj   +1 more source

Coordinated release of acylation stimulating protein (ASP) and triacylglycerol clearance by human adipose tissue in vivo in the postprandial period

Journal of Lipid Research, 1998
The objective of this study was to determine whether Acylation Stimulating Protein (ASP) is generated in vivo by human adipose tissue during the postprandial period.
Jumana Saleh, Lucinda K.M. Summers, Katherine Cianflone, Barbara A. Fielding, Allan D. Sniderman, Keith N. Frayn   +5 more
doaj   +1 more source

Extracellular Vesicle‐Transferred ATP‐Citrate Lyase Induces Monocyte Differentiation Toward Tumor‐Associated Macrophages and Fuels Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC)‐derived extracellular vesicles (EVs) enrich the metabolic enzyme ATP‐citrate lyase (ACLY). EV‐transferred ACLY enhances palmitate biosynthesis, increases the S‐palmitoylation and stability of multiple immune checkpoint proteins, augments the cellular immunosuppressive activity, and ultimately accelerates the malignant ...
Zhijun Liu, Haihong Lai, Qing Yang, Chaoyue Zhang, Bin Jia, Qiyi Chen, Yuling Deng, Fen Cao, Yuyu You, Zhe Li, Dongming Kuang, Bo Li   +11 more
wiley   +1 more source

Involvement of the Long-Chain Fatty Acid Receptor GPR40 in Depression-Related Behavior

Journal of Pharmacological Sciences, 2014
.: The functional role of brain G protein–coupled receptor 40 (GPR40) remains unclear. We investigated GPR40 signaling in depression-related behavior in mice via the forced swim test.
Takashi Nishinaka, Takuya Yamashita, Kazuo Nakamoto, Fumiyo Kasuya, Shogo Tokuyama   +4 more
doaj   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Plasma non-esterified fatty acids in patients with multiple sclerosis

, 2011
Objective: The purpose of this study was to investigate the levels of non-esterified fatty acids in plasma from patients with multiple sclerosis and further to correlate these findings with the neurological profile as measured by the Kurtzke Expanded ...
Hassan, Mogamat Shafick, Abel, Stefan, Matsha, Tandi Edith, Erasmus, Rajiv T, Hon, Gloudina Mary, Van Rensburg, Susan Janse   +5 more
core   +1 more source

Metabolic state switches between morning and evening in association with circadian clock in people without diabetes

Journal of Diabetes Investigation, 2022
Aims/Introduction Understanding morning–evening variation in metabolic state is critical for managing metabolic disorders. We aimed to characterize this variation from the viewpoints of insulin secretion and insulin sensitivity, including their relevance
Ruriko Fujimoto, Ysuharu Ohta, Konosuke Masuda, Akihiko Taguchi, Masaru Akiyama, Kaoru Yamamoto, Hiroko Nakabayashi, Yuko Nagao, Takuro Matsumura, Syunsuke Hiroshige, Yasuko Kajimura, Makoto Akashi, Yukio Tanizawa   +12 more
doaj   +1 more source

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

Advanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang, Haowei Fang, Lili Qi, Song Myoungseop, Aawrish Khan, Lunli Gong, Guangdong Zhou, Kunxi Zhang, Haiyan Cui   +8 more
wiley   +1 more source

Effect of butaphosphan and cyanocobalamin on postpartum metabolism and milk production in dairy cows

Animal, 2013
The aim of this study was to determine the effect of butaphosphan and cyanocobalamin (BTPC) supplementation on plasma metabolites and milk production in postpartum dairy cows.
R.A. Pereira, P.A.S. Silveira, P. Montagner, A. Schneider, E. Schmitt, V.R. Rabassa, L.F.M. Pfeifer, F.A.B. Del Pino, M.E. Pulga, M.N. Corrêa   +9 more
doaj   +1 more source

Influence of dietary linoleic acid intake with different fat intakes on arachidonic acid concentrations in plasma and platelet lipids and eicosanoid biosynthesis in female volunteers [PDF]

, 2003
Background/Aim: N-6 fatty acids are considered to promote diseases prevalent in industrialized countries and characterized by an increased eicosanoid biosynthesis from arachidonic acid (AA).
Zöllner, N., Adam, Olaf, Wolfram, G.
core   +1 more source