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Regulation of Insulin Clearance by Non-Esterified Fatty Acids [PDF]

open access: yesBiomedicines, 2022
Insulin stores lipid in adipocytes and prevents lipolysis and the release of non-esterified fatty acids (NEFA). Excessive release of NEFA during sustained energy supply and increase in abdominal adiposity trigger systemic insulin resistance, including in
Sonia M. Najjar   +8 more
doaj   +4 more sources

Non-esterified fatty acids and telomere length in older adults: The Cardiovascular Health Study [PDF]

open access: goldMetabolism Open, 2020
Background: Telomeres shorten as organisms age, placing limits on cell proliferation and serving as a marker of biological aging. Non-esterified fatty acids (NEFAs) are a key mediator of age-related metabolic abnormalities. We aimed to determine if NEFAs
Peter Ahiawodzi   +5 more
doaj   +3 more sources

Circulating Non-Esterified Fatty Acids as Biomarkers for Fat Content and Composition in Pigs [PDF]

open access: goldAnimals, 2021
Circulating non-esterified fatty acids (NEFA) can reflect the composition of dietary fat or adipose tissues depending on the fasting conditions. Therefore, circulating NEFA may be valuable as biomarkers for meat quality traits, such as intramuscular fat ...
Marc Tor   +8 more
doaj   +4 more sources

Non-esterified fatty acids in the ovary: friends or foes? [PDF]

open access: yesReproductive Biology and Endocrinology, 2020
A majority of common metabolic diseases can result in excessive lipolysis, leading to elevated levels of non-esterified fatty acids (NEFAs) in the body fluids.
Vijay Simha Baddela   +2 more
doaj   +2 more sources

Regulation of fibrinolysis by non-esterified fatty acids [PDF]

open access: bronzeBiochemical Journal, 1994
The ability of oleic acid to modulate fibrinolysis was measured by following the urokinase-mediated and plasminogen-dependent cleavage of 125I-labelled fibrin clots. Oleic acid levels within the physiological range exerted a concentration-dependent inhibition of urokinase-mediated fibrinolytic activity.
A A, Higazi   +3 more
openaire   +4 more sources

Longitudinal Metabolomic Profiling of Amino Acids and Lipids across Healthy Pregnancy. [PDF]

open access: yesPLoS ONE, 2015
Pregnancy is characterized by a complexity of metabolic processes that may impact fetal development and ultimately, infant health outcomes. However, our understanding of whole body maternal and fetal metabolism during this critical life stage remains ...
Karen L Lindsay   +6 more
doaj   +7 more sources

U Mass - Non-esterified fatty acids v1 [PDF]

open access: gold, 2019
Summary: This experiment measures serum and plasma concentrations of non-esterified fatty acids using a 96-well kit. The experiment involves a coupled reaction to measure non-esterified fatty acids (NEFA) which ultimately forms a purple product that absorbs light at 550nm. This allows the concentration of NEFA to be determined from the optical density
Jason Kim
openaire   +2 more sources

Adiponectin, non-esterified fatty acids and antiphospholipid antibodies in type II diabetes mellitus [PDF]

open access: diamondJournal of Medical Biochemistry, 2012
The importance of the association of antiphospholipid antibodies (aPL Abs) with the features of type II diabetes mellitus has not yet been elucidated. The aim of this work was to investigate the association of aPL Abs with adiponectin and non-esterified ...
Bećarević Mirjana   +4 more
doaj   +2 more sources

The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial [PDF]

open access: yesLipids in Health and Disease, 2018
Background Postprandial non-esterified fatty acid (NEFA) and triglyceride (TG) responses are increased in subjects with type 2 diabetes mellitus (T2DM) and may impair insulin action and increase risk of cardiovascular disease and death.
Amirsalar Samkani   +9 more
doaj   +2 more sources

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