Advanced Science, EarlyView.A macrophage–platelet conjugation system (M‐P‐NPs@PPARγ) targets injure tissue to co‐deliver platelet mitochondria and PPARγ‐encoding NPs. This strategy boosts the macrophage energy supply and restores lipid homeostasis, leading to synergistically enhanced efferocytosis and tissue repair Abstract Mitochondrial dysfunction occurs in macrophages with ...
Haoli Wang +18 more
wiley +1 more source
Changes in Body Reserves, Non-Esterified Fatty Acids, and Leptin during the Reproductive Lifespan of the Rabbit Female. [PDF]
Animals (Basel), 2023 Peiró R, Argente MJ, García ML.
europepmc +1 more source
STUDIES ON NON ESTERIFIED FATTY ACID LEVELS IN ORTHOSTIC HYPOTENSION
Nihon Naika Gakkai Zasshi, 1972 起立性低血圧の病態を血漿遊離脂肪酸(NEFA)の面から検討する目的でtilting60°による体位変換を行ない,正常血圧者および各種疾患と対比した.さらに各種起立性低血圧(高血圧性,脳血管性,糖尿病性,特発性)についても検討を行なつた.正常血圧者では, tiltingによりNEFAの上昇がみられたが,起立性低血圧ではtiltingによる交感神経系の反応が欠如し, hypotone型に比し, hypodyname型にNEFAの上昇抑制が著しく,起立による血圧下降の程度とNEFAの上昇抑制とは平行関係が認められた.疾患別では特発性のものでNEFAの抑制が最も強く,糖尿病性においては軽度であつた.さらに人為的に起立性血圧下降を惹起させると,起立性低血圧と同様なNEFAの反応を示した.治療薬として ...
openaire +2 more sources
CHANGES IN mRNA LEVELS OF INTRACELLULAR FATTY ACID METABOLISM REGULATORS IN HUMAN HEPATOMA HepG2 CELLS FOLLOWING THEIR TREATMENT WITH NON-ESTERIFIED FATTY ACIDS AND DEHYDROEPIANDROSTERONE [PDF]
, 2005 M Rypka +5 more
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Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Advanced Science, EarlyView.Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
wiley +1 more source
Fasting and Post-Load Glucose and Non-Esterified Fatty Acids and Risk of Heart Failure and Its Subtypes in Older Adults. [PDF]
J Gerontol A Biol Sci Med Sci, 2023 Oesterle A +8 more
europepmc +1 more source
Advanced Science, EarlyView.Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel +11 more
wiley +1 more source
Regulation of sphingosine-activated protein kinases: selectivity of activation by sphingoid bases and inhibition by non-esterified fatty acids [PDF]
, 1993 Pushkareva MYu +4 more
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In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases
Advanced Science, EarlyView.This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du +6 more
wiley +1 more source
Controlled method of reducing electrophoretic mobility of macromolecules, particles, or cells [PDF]
, 1992 A method of reducing electrophoretic mobility of macromolecules, particles, cells, and other substances is provided which comprises interacting in a conventional electrophoretic separating procedure, the substances with a polymer-linked affinity compound
Vanalstine, James M.
core +1 more source