Advanced Science, EarlyView.Rapamycin alleviates heart failure via TFEB and CaMKII pathways in Syntaxin 12/13 deficient models. Stx12 deficiency causes heart failure via impaired iron trafficking to mitochondria, reducing respiratory complexes and sarcoplasmic reticulum Ca2+‐ATPase (SERCA).
Run‐Zhou Yang +12 more
wiley +1 more source
Angewandte Chemie, EarlyView.We have developed a macrocyclic tetranuclear palladium complex, which has four coordination sites within its inner cavity as a host molecule. The complex captured squalene (C30H50), a linear triterpene with six C═C double bonds, through multipoint palladium‐carbon bonds, and formed a unique host‐guest complex with a folded‐squalene structure.
Kohtaro Sugawara +2 more
wiley +2 more sources
Non-Esterified Fatty Acids and Risks of Frailty, Disability, and Mobility Limitation in Older Adults: The Cardiovascular Health Study. [PDF]
J Am Geriatr Soc, 2020 Ahiawodzi P +7 more
europepmc +1 more source
Supplementation of dairy cows with propylene glycol during the periparturient period: effects on body condition score, milk yield, first estrus post-partum, beta-hydroxybutyrate, non-esterified fatty acids and glucose concentrations [PDF]
, 2004 Luís Fernando Laranja da Fonseca +4 more
openalex +1 more source
Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells [PDF]
, 2022 Yexiao Yan +4 more
openalex +1 more source
Hyperspectral Fluorescence Imaging with a New Polarity‐Ultrasensitive Fluorescent Probe
Advanced Science, EarlyView.Based on the critical role of the π‐spacer in determining wavelength sensitivity to microenvironmental polarity, a new fluorescent probe, Lipi‐PS is rationally developed, which exhibits the highest polarity‐sensitivity so far. Its integration with hyperspectral fluorescence imaging enables multiscale polarity mapping across cells, tissues, and ...
Ri Zhou +7 more
wiley +1 more source
Regioselective Hydration of Terpenes with Cofactor‐Independent Carotenoid 1,2‐Hydratase
Angewandte Chemie, EarlyView.This study reveals a highly regioselective and cofactor‐independent enzymatic approach to terpene and terpenoid hydration using a carotenoid 1,2‐hydratase from Rubrivivax gelatinosus. Beyond detailing reaction optimization strategies, an extensive substrate scope, and scale‐up potential, it explores mutagenesis and structural modeling to identify key ...
Philip Horz +6 more
wiley +2 more sources
Correlation of non-esterified fatty acids with acute coronary syndrome risk in young Chinese adults. [PDF]
Front Endocrinol (Lausanne)Wu JD +15 more
europepmc +1 more source
Pioglitazone increases non-esterified fatty acid clearance in upper body obesity [PDF]
, 2005 Samyah Shadid, Michael D. Jensen
openalex +1 more source