Results 241 to 250 of about 11,147,122 (280)

Non-HLA Antibodies in Clinical Transplantation.

Clinical transplants, 2018
Organ transplantation overcomes conservative therapy to improve patient longevity. Despite the improvement of donor-recipient compatibility tests and intensified immunosuppressive agents, long-term graft survival remains poor because of acute and chronic injury driven by immunologic and non-immunologic factors. The significant immunological barrier for
Chitranon, Chan-On, Minnie, Sarwal
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The Importance of Non-HLA Antibodies After Heart Transplant

Current Transplantation Reports, 2019
Antibodies to human leukocyte antigens (HLA) are associated with adverse patient and allograft outcomes after heart transplantation. Non-HLA antibodies have increasingly been recognized as important mediators of rejection, cardiac allograft vasculopathy (CAV), and allograft injury.
Faith Njue, Sharon Chih
openaire   +1 more source

Literature Review: The Role of Non‐HLA Antibody in Renal Transplantation

International Journal of Immunogenetics
ABSTRACT Antibodies directed to mismatched donor human leucocyte antigen (HLA‐DSA) play a well‐established role in antibody mediated rejection (AMR) and graft failure in kidney transplantation, with their presence being correlated with poorer transplant outcomes.
Charlene, Hoad, Judith, Worthington, Karen, Cosgrove, Olivia, Shaw   +3 more
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Relevance of MICA and other non-HLA antibodies in clinical transplantation

Current Opinion in Immunology, 2008
The clinical importance of HLA-specific antibodies for organ allograft outcome is well established. In the past few years, there has been an increasing interest in non-HLA antigens as targets of injury in organ transplant recipients. This increased interest has been spurred by the fact that HLA-identical kidney transplants also undergo immunological ...
openaire   +2 more sources

INHIBITION OF MLC STIMULATOR FUNCTION BY ANTIBODIES DIRECTED TO NON‐HLA ANTIGENS

International Journal of Immunogenetics, 1979
SummaryThe properties of five human alloantisera which inhibit the stimulating capacity of cells in an MLC reactions are described. All of the sera showed patterns of inhibition in families which did not correlate with HLA haplotypes. In a large proportion of the families investigated the sera did not react with parental cells but inhibited the cells ...
openaire   +3 more sources

Non-HLA antibodies in alloimmunized patients

Human Immunology, 1982
Elaine Reed, Ah-Kau Ng, Michele Pellegrino, Soldano Ferrone, Donald W. King, Nicole Suciu-Foca   +5 more
openaire   +1 more source

Non-HLA antibodies in kidney transplantation: comprehensive insights and clinical implications

Annales de Biologie Clinique
While HLA donor-specific antibodies (DSAs) are the primary mediators of allograft rejection, 20-30% of antibody-mediated rejection (ABMR) episodes occur in their absence. These 'DSA-negative' rejections represent a significant clinical challenge. This review explores the role of non-HLA antibodies (n-HLab) as potential markers of unexplained graft ...
Oumayma, Ratbi, Imane, Yakhlef, Sanae, Ouadghiri, Ouafae, Atouf, Brahim, Admou   +4 more
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Antibody–Drug Conjugates: Smart Chemotherapy Delivery Across Tumor Histologies

Ca-A Cancer Journal for Clinicians, 2022
Shanu Modi, Javier Cortes, Jean-Charles Soria   +2 more
exaly  

(1013) The Dilemma of the Role of Non-HLA Antibodies in AMR

The Journal of Heart and Lung Transplantation, 2023
M.T. Gamero, S. Marek-Iannucci, M. Liotta, Y. Huang, Y. Brailovsky, P. Uber, R. Alvarez, J. Rame, G. Gibson, E. Storozynsky, V. Tchantchaleishvili, H. Massey, K. Rajagopal, I. Rajapreyar   +13 more
openaire   +1 more source

Target cells of non-HLA antibodies in renal transplantation

Transplantation Proceedings, 1998
C, Suberbielle-Boissel, L, Mougel, H, Tolazzi, D, Charron, C, Raffoux   +4 more
openaire   +2 more sources