Results 181 to 190 of about 341,882 (288)

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

BQ323636.1 Employs the AR-CCRK Axis to Modulate the Expression of KU70 to Interfere with Non-Homologous End Joining Mediated DNA Repair Mechanism. [PDF]

Cells
Tsoi H, So ZQ, Man EPS, You CP, Cheung KH, Tse YS, Chan WL, Khoo US.   +7 more
europepmc   +1 more source

IMACulate(DE3), an E. coli Strain for High Purity His‐Tagged Protein Purifications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Immobilised Metal Affinity Chromatography (IMAC) is widely used to purify his‐tagged recombinant proteins from Escherichia coli. However, endogenous contaminants with histidine clusters, such as GFAT and PDH E1 proteins, are often co‐purified with the target protein.
Jia Q. Truong, Dingyi Yu, Nan Hao, Chris Langendorf, Keith. E. Shearwin, Jessica K. Holien   +5 more
wiley   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Improving the Efficiency of CRISPR/Cas9-Mediated Non-Homologous End Joining Gene Knockout Using Small Molecules in Porcine Cells. [PDF]

Biomolecules
Lv S, Xu X, Yang S, Feng M, Yuan Z, Liu X, Jiang C, Song J, Mu Y.   +8 more
europepmc   +1 more source

Iterative gene integration mediated by 26S rDNA and non-homologous end joining for the efficient production of lycopene in Yarrowia lipolytica. [PDF]

Bioresour Bioprocess, 2023
Luo Z, Shi JT, Chen XL, Chen J, Liu F, Wei LJ, Hua Q.   +6 more
europepmc   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Targeting synthetic lethality between non-homologous end joining and radiation in very-high-risk medulloblastoma. [PDF]

Cell Rep Med
DeCarlo A, MacLeod G, Fernandes da Silva C, Shen LQ, Povilaikaite J, Deane M, Aragao L, Sie M, Termini D, Magee J, Gudenas B, Sukumaran S, Charron F, Marcellus R, Al-Awar R, Aman A, Reynaud D, Trolat A, Wybenga-Groot L, Tabori U, Nör C, Harding SM, Moran MF, Northcott PA, Dirks P, Angers S, Ramaswamy V.   +26 more
europepmc   +1 more source

PRMT1 and PRMT5: on the road of homologous recombination and non-homologous end joining. [PDF]

Genome Instab Dis, 2023
Yin S, Liu L, Gan W.
europepmc   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source