Results 21 to 30 of about 11,318,231 (182)

Non-IgE-mediated food allergy syndromes. [PDF]

Ann Allergy Asthma Immunol, 2016
In contrast to IgE-mediated food allergies, diagnosis of the various non-IgE mediated food allergy syndromes can be challenging due to the overall lack of noninvasive confirmatory testing for these disorders. Many of the non-IgE food allergy syndromes are are diagnosed clinically, based on history and managed empirically with food avoidance. Therefore,
Ruffner MA, Spergel JM.
europepmc   +4 more sources

Nonimmunoglobulin E-Mediated Immune Reactions to Foods

Allergy, Asthma & Clinical Immunology, 2006
Adverse food reactions are abnormal responses to ingested foods. Reactions vary from immunologic to nonimmunologic immune reactions and can be either immunoglobulin E (IgE) mediated or non-IgE mediated.
Spergel Jonathan M
doaj   +1 more source

Multiplex Specific IgE Profiling in Neonatal Stool of Preterms Predicts IgE-Mediated Disease

Allergies, 2023
Background: The natural history of immunoglobulin (Ig) E-mediated diseases in preterm infants is still elusive. We aimed at developing a non-invasive tool for detecting specific IgE (sIgE) and eosinophil-derived neurotoxin (EDN) in neonatal fecal samples
Youssouf Sereme, Moïse Michel, Soraya Mezouar, Nicolas Orain, Renaud Cezar, Tran Tu Anh, Pierre Corbeau, Anne Filleron, Joana Vitte   +8 more
doaj   +1 more source

Non‐IgE mediated mast cell activation

Immunological Reviews, 2018
SummaryMast cells (MCs) are innate immune cells that are scattered in tissues throughout the organism being particularly abundant at sites exposed to the environment such as the skin and mucosal surfaces. Generally known for their role in IgE‐mediated allergies, they have also important functions in the maintenance of tissue integrity by constantly ...
Redegeld, Frank, Yu, Yingxin, Kumari, Sangeeta, Charles, Nicolas, Blank, Ulrich   +4 more
openaire   +5 more sources

Vernal keratoconjunctivitis: Current immunological and clinical evidence and the potential role of omalizumab

World Allergy Organization Journal, 2023
Vernal keratoconjunctivitis (VKC) is a severe ocular allergic disease characterized by chronic inflammation of the cornea and conjunctiva that may lead to loss of visual acuity and blindness. The disease occurs primarily in children and is more common in
Serge Doan, MD, Nikolaos G. Papadopoulos, MD, Jason K. Lee, MD, Salvatore Leonardi, MD, Sara Manti, MD, Susanne Lau, Carmen Rondon, Vibha Sharma, MD, Uwe Pleyer, MD, Xavier Jaumont, MD, Slawomir B. Lazarewicz, MD   +10 more
doaj   +1 more source

The structure of human CD23 and its interactions with IgE and CD21 [PDF]

, 2005
The low-affinity immunoglobulin E ( IgE) receptor, CD23 ( Fc epsilon RII), binds both IgE and CD21 and, through these interactions, regulates the synthesis of IgE, the antibody isotype that mediates the allergic response.
Grundy, GJ, Hibbert, R G, Peter Teriete, Jonathan P. Hannan, Brian J. Sutton, Rajko Reljić, Gould, H J, Rebecca L. Beavil, Holers, V M, Hannah J. Gould, Holers, VM, Richard G. Hibbert, McDonnell, JM, Gabrielle J. Grundy, Hibbert, RG, Sutton, BJ, James M. McDonnell, Reljic, R, V. Michael Holers, Grundy, G J, Gould, HJ, Hannan, JP, Beavil, R L, Sutton, B J, Teriete, P, Beavil, RL, McDonnell, J M; id_orcid, Hannan, J P   +27 more
core   +1 more source

Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus [PDF]

, 2008
High levels of serum IgE are considered markers of parasite and helminth exposure. In addition, they are associated with allergic disorders, play a key role in anti-tumoral defence, and are crucial mediators of autoimmune diseases.
Wichmann, H. -Erich, Ursula Krämer, Liang Liming, Markus Ollert, Stephan Weidinger, Mempel, Martin, Bauer, Carl Peter, Baurecht Hansjörg, Prokisch Holger, Mehta Divya, von Berg, A., von Mutius, Erika, Bauer Carl Peter, Gohlke, H., Cookson, W., Depner, Martin, Wagenpfeil, S., Wichmann, H.-E., Illig, T., Michael Kabesch, Mempel, M., Novak, N., Mehta, D., Illig Thomas, Liang, L., Kabesch, Michael, von Berg Andrea, Moffatt Miriam, Prokisch, H., Heinrich Joachim, Herbarth, Olf, Gohlke Henning, Bieber, Thomas, Olf Herbarth, Martin Depner, Stefan Wagenpfeil, Heinrich, Joachim, H-Erich Wichmann, Erika von Mutius, Heinrich, J., Gieger, Christian, Heidrun Behrendt, Ollert Markus, Thomas Bieber, Meitinger, T., Divya Mehta, Ring, Johannes, Rodriguez Elke, Herbarth Olf, Miriam Moffatt, Natalija Novak, von Mutius Erika, Cookson William, Mehta, Divya, Behrendt Heidrun, Klopp, Norman, Ring Johannes, Bieber Thomas, Cookson, William, Sibylle Koletzko, Meitinger Thomas, Wichmann, Heinz-Erich, Mempel Martin, Hansjörg Baurecht, William Cookson, Kraemer, Ursula, Gieger, C., Gohlke, Henning, Christian Gieger, Baurecht, H., Depner Martin, Kabesch Michael, Weidinger, S., Bieber, T., Herbarth, O., Novak, Natalija, Berdel Dietrich, Moffatt, M., Berdel, D., von Mutius, E., Koletzko, Sibylle, Klopp, N., Krämer Ursula, Gieger Christian, Liang, Liming, Bauer, C.P., Johannes Ring, Berdel, Dietrich, Wagenpfeil, Stefan, Mutius, Erika von, Koletzko Sibylle, Koletzko, S., Rodriguez, E., Krämer, U., Ollert, Markus, Ollert, M., Rodriguez, Elke, Wichmann H.-Erich, Kabesch, M., Behrendt, H., Prokisch, Holger, Moffatt, Miriam, Henning Gohlke, Carl Peter Bauer, Illig, Thomas, Meitinger, Thomas, Liming Liang, Joachim Heinrich, Andrea von Berg, Thomas Illig, Novak Natalija, von Berg, Andrea, Weidinger, Stephan, Weidinger Stephan, Klopp Norman, Baurecht, Hansjoerg, Behrendt, Heidrun, Thomas Meitinger, Depner, M., Berg, Andrea von, Dietrich Berdel, Ring, J., Wagenpfeil Stefan, Elke Rodriguez, Norman Klopp, Martin Mempel, Holger Prokisch, Weidinger, S;Gieger, C;Rodriguez, E;Baurecht, H;Mempel, M;Klopp, N;Gohlke, H;Wagenpfeil, S;Ollert, M;Ring, J;Behrendt, H;Heinrich, J;Novak, N;Bieber, T;Kramer, U;Berdel, D;von Berg, A;Bauer, CP;Herbarth, O;Koletzko, S;Prokisch, H;Mehta, D;Meitinger, T;Depner, M;von Mutius, E;Liang, L;Moffatt, M;Cookson, W;Kabesch, M;Wichmann, HE;Illig, T   +127 more
core   +1 more source

World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guideline update – VII – Milk elimination and reintroduction in the diagnostic process of cow's milk allergy

World Allergy Organization Journal, 2023
The diagnosis of cow's milk allergy (CMA) in infants and young children remains a challenge because many of the presenting symptoms are similar to those experienced in other diagnoses. Both over- and under-diagnosis occur frequently. Misdiagnosis carries
Rosan Meyer, RD, PhD, Carina Venter, RD, PhD, Antonio Bognanni, MD, PhD(s), Hania Szajewska, MD, PhD, Raanan Shamir, MD, PhD, Anna Nowak-Wegrzyn, MD, PhD, Alessandro Fiocchi, MD, PhD, Yvan Vandenplas, MD, PhD   +7 more
doaj   +1 more source

Non-IgE-mediated drug-induced hypersensitivity reactions in pediatrics. [PDF]

Curr Opin Pediatr
Purpose of review Despite their prevalence and potential severity, non-IgE-mediated drug-induced hypersensitivity reactions (DHRs) are under-researched and poorly defined, particularly in children. Presentations range from mild cutaneous reactions to severe systemic diseases, with pathophysiological mechanisms and reliable ...
Chow TG, Muzaffar AF, Alvarez-Arango S.
europepmc   +4 more sources

Cephalosporin Induced Toxic Epidermal Necrolysis and Subsequent Penicillin Drug Exanthem

Allergology International, 2008
Background: Drug hypersensitivity is classically divided into IgE mediated and non-IgE mediated disease. We report a rare case of consequent IgE mediated and non-IgE mediated reactions within the beta lactam class of antibiotics. Case Summary: An 84-year-
Amanda Lam, Inderpal Randhawa, William Klaustermeyer   +2 more
doaj   +1 more source