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Prodromal non-motor symptoms of Parkinson's disease [PDF]

Neuropsychiatric Disease and Treatment, 2007
The motor symptoms of Parkinson's disease (PD), bradykinesia, muscular rigidity, and tremor depend upon degeneration of the dopaminergic neurons in the substantia nigra pars compacta. Recent neuropathological studies show that the Lewy bodies, the intraneuronal landmark of PD, accumulate in several neuronal cell types in the brain.
PELLICANO, CLELIA, BENINCASA, DARIO, PISANI V, BUTTARELLI, Francesca Romana, GIOVANNELLI M, PONTIERI, FRANCESCO ERNESTO   +5 more
openaire   +3 more sources

Relation of Apathy to Motor and Non-motor Findings in Parkinson’s Disease

Haseki Tıp Bülteni, 2019
Aim:It has been shown that motor symptoms, as well as non-motor symptoms, significantly affect the quality of life of patients with idiopathic Parkinson’s disease. In our study, the association of apathy, one of the NMS, with motor and non-motor symptoms
Melek Gürbüz, Gönül Akdağ, Özge Arıcı Düz, Feriha Özer, Özlem Çokar, Lütfü Hanoğlu   +5 more
doaj   +1 more source

Remote Assessment of Parkinson’s Disease Patients Amidst the COVID-19 Lockdown in Mexico

Brain Sciences, 2023
The COVID-19 pandemic introduced unprecedented challenges in managing patients with Parkinson’s disease (PD) due to disruptions in healthcare services and the need for social distancing. Understanding the effects of COVID-19 on PD symptoms is crucial for
Rodrigo León-García, Emmanuel Ortega-Robles, Oscar Arias-Carrión   +2 more
doaj   +1 more source

Fatigue in patients with Parkinson’s disease: Motor and Non-motor Clinical Associations

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2017
Objective: Fatigue is one of the common non-motor symptoms of Parkinson’s disease (PD). In this study, we aimed to investigate the prevalence of fatigue in PD patients and to determine the fatigue-related demographic, motor and non-motor disease ...
Bilge Gönenli Koçer, Erhan Arif Öztürk, Selim Selçuk Çomoğlu   +2 more
doaj   +1 more source

Sleep quality in patients with Parkinson’s disease in the Republic of Moldova – preliminary results [PDF]

Romanian Journal of Neurology
Background and objectives. The rising prevalence of sleep issues are a consequent societal problem, notably impacting individuals with Parkinson’s disease (PD).
Lilia Rotaru, Madalina Cebuc, Oxana Grosu, Adrian Lupusor, Ion Moldovanu, Stela Odobescu, Svetlana Lozovanu, Victor Vovc, Ghenadie Carausu, Stanislav Groppa   +9 more
doaj   +1 more source

Longitudinal analysis of the Non-Motor Symptoms Scale in Parkinson's Disease (NMSS): An exploratory network analysis approach

Frontiers in Neurology, 2023
IntroductionParkinson's disease (PD) is a multisystem neurodegenerative disorder characterized by motor and non-motor symptoms. In particular, non-motor symptoms have become increasingly relevant to disease progression.
Konstantin G. Heimrich, Aline Schönenberg, Hannah M. Mühlhammer, Hannah M. Mühlhammer, Sarah Mendorf, Diego Santos-García, Tino Prell   +6 more
doaj   +1 more source

Lipopolysaccharide animal models of Parkinson’s disease: Recent progress and relevance to clinical disease

Brain, Behavior, & Immunity - Health, 2020
Parkinson’s disease (PD) is one of the most common neurodegenerative movement disorders which is characterised neuropathologically by progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the presence of Lewy bodies ...
Isaac Deng, Frances Corrigan, Guangxi Zhai, Xin-Fu Zhou, Larisa Bobrovskaya   +4 more
doaj   +1 more source

Self-Reported Motor and Non-Motor Symptoms in People With Functional Gait Disorder: A Cross-Sectional Study. [PDF]

Brain Behav
Issak S, Williams G, Kanaan RA, Fini NA, Nielsen G.   +4 more
europepmc   +3 more sources

Non-motor symptoms in Parkinson's disease [PDF]

Arquivos de Neuro-Psiquiatria, 2013
he classic features of the clinical picture in Parkinson’s disease (PD) are the motor disorders: akinesia, rigidity, tremor and postural instability. However, non-motor symptoms (NMS) are frequently present. Therefore, patients with PD can present, besides the typical parkinsonian motor syndrome, a wide arrow of NMS, mainly neuropsychiatric ...
openaire   +3 more sources

A Review of the Relationship Between Vitamin D and Parkinson Disease Symptoms

Frontiers in Neurology, 2020
Vitamin D is a fat-soluble secosteroid that exerts its effects by binding to the vitamin D receptor (VDR), through which it directly and indirectly modulates the expression of hundreds to thousands of genes.
Michelle E. Fullard, John E. Duda, John E. Duda   +2 more
doaj   +1 more source