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Non-nutritive Sweeteners and Human Bladder Cancer: Preliminary Findings
Journal of Urology, 1976The non-nutritive sweeteners, saccharin and cyclamate, were not associated with the risk of human bladder cancer in a controlled investigation. The prior intake of such sweeteners in any and all forms was not greater or more prolonged among 209 recently diagnosed bladder cancer patients than among 209 otherwise similar patients without bladder disease.
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Non-nutritive Sweeteners and Reward Mechanisms
Abstract Over the past several decades, rates of diet-related chronic diseases have risen dramatically, posing a significant public health concern. In an effort to reduce sugar intake and promote weight management, non-nutritive sweeteners are increasingly utilized as a dietary substitute for nutritive sugar consumption, to satiate the ...Kathleen A. Page, Alexandra G. Yunker
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How do non-nutritive sweeteners increase food intake?
Appetite, 1988In short-term tests, rats given saccharin solution to drink eat 10-15% more food than when given only water. This is due to the combination of a cephalic-phase neural reflex that influences liver metabolism, a favorable osmotic environment and learning.
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Biochemical and Biophysical Research Communications - BBRC, 2021
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