Results 61 to 70 of about 6,251 (285)

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

Advanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner, Vladimir Perlis, Eran Golden, Ariel Pokhojaev, Rachel Sarig, Itzhak Binderman, Michal Halperin‐Sternfeld, Solomon Dadia, Lihi Adler‐Abramovich   +8 more
wiley   +1 more source

Stevia derivative and its potential uses in diabetic-directed foods. Review [PDF]

, 2016
Diabetes has been contextualized as pandemic, but market supplying their food does not seem to grow in parallel with the problem. There are many substances on the market that will be useful as ingredients to produce foods for diabetic consumers, focusing
González, Cesar, Lares, Mary, Perez, Elevina, Vaillant, Fabrice   +3 more
core   +1 more source

Edible Pneumatic Battery for Sustained and Repeated Robot Actuation

Advanced Science, EarlyView.
This work presents an edible energy source and valve system to power soft, pneumatically driven edible robots. A chemical reaction between sodium bicarbonate and citric acid generates carbon dioxide gas, and a pressure‐triggered edible valve enables self‐repetitive motion of the edible actuator.
Bokeon Kwak, Shuhang Zhang, Alexander Keller, Qiukai Qi, Jonathan Rossiter, Dario Floreano   +5 more
wiley   +1 more source

Palladium-Catalyzed ortho-Arylation of Carbamate-Protected Estrogens [PDF]

, 2016
The palladium-catalyzed ortho-arylation of diethylcarbamate-protected estrone and estriol with aryl iodides, gives the 2-arylated analogues. Subsequent removal of the carbamate directing group furnishes 2-arylated estrone, estradiol or estriol depending ...
Bedford, Robin B, Brenner, Peter B, Durrant, Steven J, Gallagher, Timothy, Montgomery, Michelle, Méndez-Gálvez, Carolina   +5 more
core   +2 more sources

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Process Simulation and Techno-Economic Analysis of Large-Scale Bioproduction of Sweet Protein Thaumatin II

Foods, 2021
There are currently worldwide efforts to reduce sugar intake due to the various adverse health effects linked with the overconsumption of sugars. Artificial sweeteners have been used as an alternative to nutritive sugars in numerous applications; however,
Kirolos D. Kelada, Daniel Tusé, Yuri Gleba, Karen A. McDonald, Somen Nandi   +4 more
doaj   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

Advanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao, Zhihao Wang, Shasha Tang, Yuan Fang, Guiling Yu, Xiaoting Qiu, Lingxue Niu, Tao Yan, Xingwan Liu, Xiaoding Ma, Deqiang Kong, Yang Zhou, Ningzi Guan, Jinzhong Tian, Meiyan Wang, Haifeng Ye, Fengfeng Cai   +16 more
wiley   +1 more source

Efecto de la suplementación de edulcorantes naturales y artificiales sobre el perfil histomorfológico y la distribución corporal del tejido adiposo en el ratón BALB/c [PDF]

, 2017
with the indiscriminate consumption of non-nutritive sweeteners (NNS) an increase of adipose tissue has been observed, even though these products do not directly participate in the generation of metabolic energy.
SOSA GARCIA, BETSY CORINA, SOSA GARCIA, BETSY CORINA   +1 more
core  

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source