Results 61 to 70 of about 6,272 (286)

Stevia derivative and its potential uses in diabetic-directed foods. Review [PDF]

open access: yes, 2016
Diabetes has been contextualized as pandemic, but market supplying their food does not seem to grow in parallel with the problem. There are many substances on the market that will be useful as ingredients to produce foods for diabetic consumers, focusing
González, Cesar   +3 more
core   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

open access: yesAdvanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao   +16 more
wiley   +1 more source

Az energiamentes édesítőszerek hatása az egyes anyagcsere-paraméterekre [PDF]

open access: yes, 2016
Absztrakt Az energiamentes édesítőszerek az üdítőitalok mellett számos egyéb élelmiszerben is megtalálhatók.
Hidvégi, Tibor
core   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

open access: yesAdvanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li   +13 more
wiley   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

open access: yesAdvanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao   +6 more
wiley   +1 more source

Palladium-Catalyzed ortho-Arylation of Carbamate-Protected Estrogens [PDF]

open access: yes, 2016
The palladium-catalyzed ortho-arylation of diethylcarbamate-protected estrone and estriol with aryl iodides, gives the 2-arylated analogues. Subsequent removal of the carbamate directing group furnishes 2-arylated estrone, estradiol or estriol depending ...
Bedford, Robin B   +5 more
core   +2 more sources

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

open access: yesAdvanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang   +11 more
wiley   +1 more source

Evidence supporting oral sensitivity to complex carbohydrates independent of sweet taste sensitivity in humans. [PDF]

open access: yesPLoS ONE, 2017
Compared to simple sugars, complex carbohydrates have been assumed invisible to taste. However, two recent studies proposed that there may be a perceivable taste quality elicited by complex carbohydrates independent of sweet taste.
Julia Y Q Low   +3 more
doaj   +1 more source

Process Simulation and Techno-Economic Analysis of Large-Scale Bioproduction of Sweet Protein Thaumatin II

open access: yesFoods, 2021
There are currently worldwide efforts to reduce sugar intake due to the various adverse health effects linked with the overconsumption of sugars. Artificial sweeteners have been used as an alternative to nutritive sugars in numerous applications; however,
Kirolos D. Kelada   +4 more
doaj   +1 more source

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