Results 91 to 100 of about 10,367,564 (257)

La presencia del caos en un mundo determinista

open access: yesCuestiones de Filosofía, 2022
La ciencia moderna estableció una serie de procedimientos para conocer la realidad, basados en parámetros entre los que se destacan el uso del método analítico de Descartes, las herramientas de la mecánica newtoniana y la confianza en modelos ...
Graciela Chaparro, Roberto Ávila
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Analytical building thermology: framework, methodology and applications

open access: yesCarbon Neutrality
Buildings consumed 32% global energy and emitted 34% CO2 in 2023, while indoor air pollution caused over 3.2 million premature deaths in 2020. Creating low-carbon and healthy buildings is of great significance to sustainable development.
Pengcheng Ji   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Quantum Field Theory and the Limits of Reductionism [PDF]

open access: yes
I suggest that the current situation in quantum field theory (QFT) provides some reason to question the universal validity of ontological reductionism.
Adlam, Emily
core   +3 more sources

Czy podmiotowość epistemiczna ma znaczenie moralne? (DOES EPISTEMIC SUBJECTIVITY HAVE MORAL IMPORT?) [PDF]

open access: yesAnaliza i Egzystencja, 2007
We start from the basics: there is a meaning of the notion of epistemic subject under which it is not an object at all. This statement does not lead to dualism of substance; it fits with any sort of non-reductionism.
Piotr Bołtuć
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The Problems with Genetic Essentialism, Determinism, and Reductionism

open access: yes
In this article, we address misunderstandings about genetic essentialism, genetic determinism, and genetic reductionism. There are good reasons to carefully consider the meanings and relationships that characterize genetic essentialism, genetic ...
Moore, David S.   +5 more
core   +1 more source

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