Results 101 to 110 of about 7,040,883 (266)
La presencia del caos en un mundo determinista
Cuestiones de Filosofía, 2022 La ciencia moderna estableció una serie de procedimientos para conocer la realidad, basados en parámetros entre los que se destacan el uso del método analítico de Descartes, las herramientas de la mecánica newtoniana y la confianza en modelos ...
Graciela Chaparro, Roberto Ávila
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Justification of Testimonial Belief——New ways of Transcending Reductionism vs Non-Reductionism and Supplement to These Approaches [PDF]
, 2017 Testimony被视为一个重要的知识来源。Testimony信念的确证是testimony知识论中的一个基本问题。对于这个问题,知识论学者们长期争论不休,主要分为还原论和非还原论两种主张,但这两种主张都面临难着以解决的困难。不过,近十年来出现了两个很有创见的新理论,即詹妮弗·拉基(Jennifer Lackey)和保罗·福克纳(Paul Faulkner)分别所提出的testimony信念确证的理论。这两个理论是对还原论和非还原论的片面性的超越,这是文章重点论述的。此外,针对这两种新理论 ...
孟峰
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Two Forms of Functional Reductionism in Physics [PDF]
, 2022 Functional reductionism characterises inter-theoretic reduction as the recovery of the upper-level behaviour described by the reduced theory in terms of the lower-level reducing theory.
Lorenzetti, Lorenzo
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Religious Belief, Evidentialism, and Skeptical Theism
Cuestiones Teológicas, 2016 The purpose of the article is to develop a line of argument in favor of a religious belief in the existence of God, in such a way that it is possible to hold that: i) it is a rational belief and ii) it is non-dependent on contingent evidence.
Rafael Felipe Miranda Rojas
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Non-eliminative Reductionism: Reconciling Qualia and Physicalism. [PDF]
A physicalist view of qualia labelled non-eliminative reductionism is outlined. If it is true, qualia and physicalism can co-exist without difficulty. First, qualia present no particular problem for reductionist physicalism - they are entirely physical ...
Nicholson, Dennis
core +1 more source
Kripkenstein and Non-Reductionism about Meaning-Facts [PDF]
, 2009 In 1982 Saul A. Kripke proposed a reconstruction of the central insights of Ludwig Wittgenstein's remarks on rule-following. The reconstruction prominently featured a sceptical challenge which soon was recognised as a new and very radical form of ...
Demont, Florian
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