Results 101 to 110 of about 7,040,880 (266)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Czy podmiotowość epistemiczna ma znaczenie moralne? (DOES EPISTEMIC SUBJECTIVITY HAVE MORAL IMPORT?) [PDF]
Analiza i Egzystencja, 2007 We start from the basics: there is a meaning of the notion of epistemic subject under which it is not an object at all. This statement does not lead to dualism of substance; it fits with any sort of non-reductionism.
Piotr Bołtuć
doaj
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
, 1998 In the article three types of reductionism are discussed: i) ontological reductionism (what happens on the «higher» level is causally determined by what happens on the «lower» level; ii) epistemological (the knowledge about the world can in principle be ...
Kałuszyńska, Elżbieta
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
O testemunho como fonte de justificação: um estudo sobre a epistemologia do testemunho [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Hmanas, Programa de Pós-Graduação em Filosofia, Florianópolis, 2013.O principal problema da epistemologia do testemunho é investigar a justificação que o ...
Moreira, Delvair Custódio
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The spiritual core of the hard problem: consciousness as foundational, not emergent
Frontiers in PsychologyThis paper proposes a transpersonal reframing of the Hard Problem of Consciousness by positing that consciousness is ontologically primary—not an emergent property of neural processes, but the foundational reality from which mind and matter arise ...
Amira Arora
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Science or Mind? Reductionism Proper, Optimal Reductionism, and Emergent Interactionism
, 2009 Some reflections about reductionism in ...
Capitelli M +3 more
core