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The Research on Naturalistic Non-Reductionism in Metaethics [PDF]

open access: yes, 2010
伦理自然主义非还原论是一种承认道德性质、道德事实真实存在的道德实在论。它反对将道德性质、道德事实还原为自然性质、自然事实,也反对将道德语言重新定义为自然语言。它不是摩尔在《伦理学原理》中批评的那种自然主义,是异于直觉主义和自然主义还原论的特殊理论。The non-reductionism in ethical naturalism is a kind of moral realism which acknowledges the real existence of moral properties ...
杨松
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Three concepts of power: Foucault, Bourdieu, and Habermas

open access: yesPower and Education
The article is a discussion of the concept of power in three different social theories that are often applied to educational research: the theories of Jürgen Habermas, Pierre Bourdieu, and Michel Foucault.
Gerd Christensen
doaj   +1 more source

TRANSFORMATION OF THE PARADIGM OF WRITING BIOGRAPHIES: A META-CRITICAL SYNTHESIS OF CONTEMPORARY LITERATURE AND BIOGRAPHICAL STUDIES

open access: yesJurnal Ceteris Paribus
This article presents a meta-critical synthesis of the paradigm shifts in life writing—encompassing both biography and autobiography—as documented in thirteen (13) articles published in the journal Biography between 1972 and 1979.
Yudhi Andoni, Febbrizal, Novi Yulia
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Mind-Body Causal Relationship: Inquiry into Mental Health Disorders and the Limits of Neurobiological Reductionism

open access: yesIbom Medical Journal
This paper undertook a critical and exploratory inquiry into how causality in the mind-body relationship has been theorised and operationalised in contemporary mental health discourse. Unlike dominant approaches that prioritised brain-based explanations
Archibong EI   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

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