The non-specific effects of vaccines in low income countries [PDF]
In their commentary on my article about the non-specific effects of vaccines, Paul Fine and David Elliman state that we are dealing with ‘unproven non-specific effects’ and imply that these effects may not be of widespread importance because ‘much of the evidence’ comes from Guinea-Bissau.1 First, proof is never possible in medicine.
Frank Shann
openalex +3 more sources
Australia, immunisation, GAVI, and the non‐specific effects of vaccines [PDF]
Frank Shann
doaj +3 more sources
Beneficial non-specific effects of live vaccines against COVID-19 and other unrelated infections [PDF]
Live attenuated vaccines could have beneficial, non-specific effects of protecting against vaccine-unrelated infections, such as BCG protecting against respiratory infection. During the COVID-19 pandemic, testing of these effects against COVID-19 was of interest to the pandemic control programme.
Peter Aaby +2 more
openalex +4 more sources
Commentary: Non-specific effects of measles vaccine—more grist for the mill [PDF]
Paul Fine
openalex +3 more sources
Background: West African studies have suggested that national immunisation campaigns with oral polio vaccine (C-OPV) may non-specifically reduce all-cause child mortality rate by 15–25%.
Sebastian Nielsen +4 more
doaj +1 more source
P-1430. Does BCG Vaccine Result in Non-Specific Effects on Childhood Infections in American Indian and Alaska Native Children? [PDF]
Andrew W Hill +4 more
europepmc +2 more sources
Beneficial Non‐Specific Effects of Measles Vaccine: Fact or Fiction?
Background: A recent Systematic Review claimed that randomised controlled trials (RCTs) showed that there are no beneficial non-specific effects (NSEs) of measles vaccine (MV); i.e. effects not explained by prevention of measles infection. The claim contradicts previous meta-analyses. Methods: We examined the reasons for these contradictory views.
Sebastian Nielsen +4 more
openalex +3 more sources
Oral Polio Vaccine Campaigns May Reduce the Risk of Death from Respiratory Infections
Oral polio vaccine (OPV) campaigns, but not other campaigns, have been associated with major reductions in child mortality. Studies have shown that OPV reduces the risk of respiratory infections.
Sebastian Nielsen +4 more
doaj +1 more source
Complement-Mediated Virus Infectivity Neutralisation by HLA Antibodies Is Associated with Sterilising Immunity to SIV Challenge in the Macaque Model for HIV/AIDS. [PDF]
Sterilising immunity is a desired outcome for vaccination against human immunodeficiency virus (HIV) and has been observed in the macaque model using inactivated simian immunodeficiency virus (SIV).
A Morner +61 more
core +8 more sources
Background Measles vaccination coverage in Guinea-Bissau is low; fewer than 80% of children are currently measles vaccinated before 12 months of age. The low coverage hampers control of measles.
Ane B. Fisker +5 more
doaj +1 more source

