Results 121 to 130 of about 1,616,230 (293)
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Numerous organic chemicals are present in aquatic environments, yet systematically identifying and prioritizing these compounds remains a major challenge, particularly in tropical island watersheds where data are scarce.
Zhongyuan Gao +12 more
doaj +1 more source
Innovations that Address Socioeconomic, Cultural, and Geographic Barriers to Preventive Oral Health Care [PDF]
This report focuses on nine oral health innovations that integrate service delivery and workforce models in order to reduce or eliminate socioeconomic, geographic, and cultural barriers to care.
D. Krol +4 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Non-target screening to track contaminant removal and release during nature-based water treatment
Introduction: Population growth and increasing water demand have exacerbated water resource scarcity. Treated wastewater (TWW) is a valuable alternative resource, but its complex composition, including micropollutants, raises concerns about reuse risks ...
Charlotte Guy +4 more
doaj +1 more source
Fusion reactions in plasmas as probe of the high-momentum tail of particle distributions
In fusion reactions, the Coulomb barrier selects particles from the high-momentum part of the distribution. Therefore, small variations of the high-momentum tail of the velocity distribution can produce strong effects on fusion rates.
Coraddu, Massimo +3 more
core +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Suspect and non-target screening of contaminants of emerging concern in Norwegian biogas digestates
To achieve a circular bioeconomy, nutrients within residues such as food waste (FW) and sewage sludge (SS) must be recycled to e.g., food production. However, these biowastes often contain numerous contaminants which are recycled alongside the nutrients.
Aasim M. Ali +7 more
doaj +1 more source

