Objectives The objective of this study was to evaluate the performance of non‐targeted hepatitis C virus (HCV) screening in emergency departments (EDs) and other healthcare settings in terms of patients identified with HCV infection and linked to HCV ...
Cody A. Chastain +13 more
doaj +1 more source
The recent advances of novel methodologies such as non-targeted and suspect screening based on high-resolution mass spectrometry (HRMS) have paved the way to a new paradigm for exposure assessment.
Juliana Monteiro Bastos da Silva +5 more
doaj +1 more source
The association between socio-demographic characteristics and adherence to breast and colorectal cancer screening: Analysis of large sub populations [PDF]
Background Populations having lower socioeconomic status, as well as ethnic minorities, have demonstrated lower utilization of preventive screening, including tests for early detection of breast and colorectal cancer.
Rachel Wilf-Miron +6 more
core +1 more source
Exposomic Biomonitoring of Polyphenols by Non-Targeted Analysis and Suspect Screening
Polyphenols, prevalent in plants and fungi, are investigated intensively in nutritional and clinical settings because of their beneficial bioactive properties. Due to their complexity, analysis with untargeted approaches is favorable, which typically use high-resolution mass spectrometry (HRMS) rather than low-resolution mass spectrometry (LRMS).
Ian Oesterle +6 more
openaire +2 more sources
Sample preparation techniques for suspect and non-target screening of emerging contaminants [PDF]
The progress in sensitivity and resolution in mass spectrometers in recent years provides the possibility to detect a broad range of organic compounds in a single procedure. For this reason, suspect and non-target screening techniques are gaining attention since they enable the detection of hundreds of known and unknown emerging contaminants in various
Parvaneh Hajeb +3 more
openaire +2 more sources
Patient-centric trials for therapeutic development in precision oncology [PDF]
An enhanced understanding of the molecular pathology of disease gained from genomic studies is facilitating the development of treatments that target discrete molecular subclasses of tumours.
A Hollebecque +60 more
core +1 more source
Influence of providers and nurses on completion of non-targeted HIV screening in an urgent care setting [PDF]
Introduction: Despite recommendations by the Centers for Disease Control (CDC) that all adults be offered non-targeted HIV screening in all care settings, screening in acute-care settings remains unacceptably low.
Bender Ignacio, Rachel A +6 more
core +2 more sources
Evaluation of Phage Display Discovered Peptides as Ligands for Prostate-Specific Membrane Antigen (PSMA) [PDF]
The aim of this study was to identify potential ligands of PSMA suitable for further development as novel PSMA-targeted peptides using phage display technology. The human PSMA protein was immobilized as a target followed by incubation with a 15-mer phage
A Ghosh +48 more
core +7 more sources
EPMA position paper in cancer:current overview and future perspectives [PDF]
At present, a radical shift in cancer treatment is occurring in terms of predictive, preventive, and personalized medicine (PPPM). Individual patients will participate in more aspects of their healthcare.
Bubnov, Rostylav +7 more
core +5 more sources
Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy. [PDF]
Current cell-free DNA (cfDNA) next generation sequencing (NGS) precision oncology workflows are typically limited to targeted and/or disease-specific applications.
Alva, Ajjai S +31 more
core +1 more source

