Results 101 to 110 of about 333,820 (286)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Strong Correlations Between Fluctuations and Response in Aging Transport

, 2006
Once the problem of ensemble averaging is removed, correlations between the response of a single molecule to an external driving field $F$, with the history of fluctuations of the particle, become detectable.
E. Barkai, E. Barkai, M. V. Feigelman
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Response Function of Coarsening Systems

, 1999
The response function of domain growth processes, and in particular the violation of the fluctuation-dissipation theorem, are studied both analytically and numerically.
Barrat, Jean-Louis, Berthier, Ludovic, Kurchan, Jorge   +2 more
core   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Effect of intrinsic heat treatment on the microstructure and mechanical properties of Al-Cu alloy fabricated by wire arc directed energy deposition

Scientific Reports
Wire arc directed energy deposition (WADED) represents an appealing approach for producing complex, large-scale, and three-dimensional metallic components from metallic wire, guided by computer-aided design models.
Bin Yang, Xiaodong Li, Shuang Lei, Yating Li, Xinyuan Jin, Guoping Zhao, Xianfeng Li   +6 more
doaj   +1 more source

Multistability in Large Scale Models of Brain Activity.

PLoS Computational Biology, 2015
Noise driven exploration of a brain network's dynamic repertoire has been hypothesized to be causally involved in cognitive function, aging and neurodegeneration.
Mathieu Golos, Viktor Jirsa, Emmanuel Daucé   +2 more
doaj   +1 more source

Mathematical analysis of a one-dimensional model for an aging fluid

, 2012
We study mathematically a system of partial differential equations arising in the modelling of an aging fluid, a particular class of non Newtonian fluids.
Benoit, David, Bris, Claude Le, He, Lingbing, Lelièvre, Tony   +3 more
core   +3 more sources

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Maturing Mycobacterium smegmatis peptidoglycan requires non-canonical crosslinks to maintain shape

eLife, 2018
In most well-studied rod-shaped bacteria, peptidoglycan is primarily crosslinked by penicillin-binding proteins (PBPs). However, in mycobacteria, crosslinks formed by L,D-transpeptidases (LDTs) are highly abundant.
Catherine Baranowski, Michael A Welsh, Lok-To Sham, Haig A Eskandarian, Hoong Chuin Lim, Karen J Kieser, Jeffrey C Wagner, John D McKinney, Georg E Fantner, Thomas R Ioerger, Suzanne Walker, Thomas G Bernhardt, Eric J Rubin, E Hesper Rego   +13 more
doaj   +1 more source