Results 91 to 100 of about 333,820 (286)

Generalized Lyapunov exponent as a unified characterization of dynamical instabilities

, 2014
The Lyapunov exponent characterizes an exponential growth rate of the difference of nearby orbits. A positive Lyapunov exponent is a manifestation of chaos.
Aizawa, Yoji, Akimoto, Takuma, Nakagawa, Masaki, Shinkai, Soya   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Aging Exacerbates Restraint Stress-Induced Inhibition of Antigen-Specific Antibody Production in Mice

Allergology International, 2009
Background: We have recently found that exposure to acute restraint stress suppresses antigen-specific antibody production, including IgE, in a murine model of allergic rhinitis.
Yumiko Ichihara, Mitsuhiro Okano, Keiko Nishioka, Noriko Manabe, Naoto Ichihara, Fumihiko Jitsunari, Tazuko Fujiwara, Kazunori Nishizaki   +7 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The aging immune system and all-cause mortality in older americans: differences across sex and race/ethnicity

Immunity & Ageing
Background As individuals age, the immune system undergoes complex changes, including an increase in the number of CD8 T cells relative to CD4 T cells, a decline in naïve cell production (including T and B cells), and an accumulation of terminally ...
Kate A. Duchowny, Yuan S. Zhang, Rebecca C. Stebbins, Xin Ma, Jaydon Jun Yu Chin, Virginia W. Chang, Allison E. Aiello, Grace A. Noppert   +7 more
doaj   +1 more source

Development and Open-Source Implementation of JOS-3: A Human Thermoregulation Model for Diverse Environmental Applications [PDF]

E3S Web of Conferences
Accurate evaluation of human thermal comfort is essential for designing thermally acceptable environments. While widely used indices such as Predicted Mean Vote (PMV) and Standard New Effective Temperature (SET*) perform well under uniform and steady ...
Tanabe Shin-ichi
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Editorial: Tendon Structure-Function Relationship in Health, Ageing, and Injury

Frontiers in Sports and Active Living, 2021
Huub Maas, Toni Arndt, Jason R. Franz
doaj   +1 more source

Flexible Grouping for Enhanced Energy Utilization Efficiency in Battery Energy Storage Systems

Energies, 2016
As a critical subsystem in electric vehicles and smart grids, a battery energy storage system plays an essential role in enhancement of reliable operation and system performance.
Weiping Diao, Jiuchun Jiang, Hui Liang, Caiping Zhang, Yan Jiang, Leyi Wang, Biqiang Mu   +6 more
doaj   +1 more source