Results 71 to 80 of about 333,820 (286)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

A Simple Analytic Method to Model and Detect Non-Uniform Air-Gaps in Synchronous Generators

open access: yesIranian Journal of Electrical and Electronic Engineering, 2010
The air-gap of electrical machines may become non-uniform due to low accuracy of the manufacturing machinery, in assembling processes, or by aging. Detection and monitoring of this phenomenon is very important and of interest.
A. Damaki Aliabad   +2 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Marzke-Wheeler coordinates for accelerated observers in special relativity [PDF]

open access: yes, 2000
In special relativity, the definition of coordinate systems adapted to generic accelerated observers is a long-standing problem, which has found unequivocal solutions only for the simplest motions.
Pauri, Massimo, Vallisneri, Michele
core   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The ALICE Muon IDentifier

open access: yes, 2020
During the LHC Run-I (2010-2013) and Run-II (2015-2018), the selection of interesting events for muon physics in ALICE was performed with a dedicated muon trigger system, based on 72 single-gap bakelite Resistive Plate Chambers (RPCs), operated in maxi ...
Terlizzi, Livia
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Characterization of long-term field aging: differential impacts on rheological, chemical, and morphological properties of binders across the lanes of flexible pavement

open access: yesInternational Journal of Transportation Science and Technology
Field aging is a complicated process wherein the binder ages inevitably due to the synergic effects of temperature, humidity, pressure, ultraviolet (UV) rays, and oxidation that occur in the field, and has a significant impact on the service life of ...
S. Tejeshwini, K.H. Mamatha, S.V. Dinesh
doaj   +1 more source

Quantification of Damage Progression in a Thermally Aged Duplex Stainless Steel

open access: yesMaterials Research, 2002
Ferrite of austeno-ferritic stainless steels maintained for a long time at temperatures in the range of 270 °C to 400 °C is embrittled like the known 475 °C embrittlement of ferritic stainless steels.
A. Hazarabedian, B. Marini
doaj   +1 more source

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