Results 51 to 60 of about 131,930 (291)

Investigating the structural dynamics and crack propagation behavior under uniform and non-uniform temperature conditions [PDF]

open access: yes, 2021
The robustness and stability of the system depend on structural integrity. This stability is, however, compromised by aging, wear and tear, overloads, and environmental factors. A study of vibration and fatigue cracking for structural health monitoring
Kamei, Khangamlung   +3 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

How Non-Uniform Temperatures Influence the Performance and Ageing of Lithium-Ion Batteries

open access: yes, 2021
Lithium-Ionen Batterien (LIB) finden aufgrund ihrer Vorteile hinsichtlich Energie- und Leistungsdichte sowie ihrer Zuverlässigkeit verbreitete An-wendung als elektrochemische Energiespeicher. Sie spielen im Rahmen des Klimawandels und der dadurch bedingten Energiewende eine zentrale Rolle in der Elektrifizierung der Mobilität.
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Study on the Electroacoustic Pulse Method for Space Charge Recovery Algorithm Considering Temperature Gradient Aging

open access: yesEnergies
This study addresses the impact of temperature gradient-induced non-uniform aging on the accuracy of space charge measurements in cross-linked polyethylene (XLPE) insulation for high-voltage direct-current cables.
Jia Chu, Yanqing Li, Heng Yang, Tao Han
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

NIOSH National Center for Productive Aging and Work [PDF]

open access: yes
"What are our priorities? The National Institute for Occupational Safety and Health (NIOSH) National Center for Productive Aging and Work (NCPAW) works with partners in industry, labor, trade associations, professional organizations, and academia.

core   +1 more source

Non-Response to Population Aging in Sub-Saharan Africa: A Survey of Gerontology Scholars

open access: yes, 2021
Life expectancy is increasing globally, with the biggest gains expected in sub-Saharan Africa. In fact, most of the population growth globally in the next few decades will occur in sub-Saharan Africa.
Adamek, Margaret   +3 more
core   +1 more source

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