Results 51 to 60 of about 11,105,791 (289)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
CeramicsThe shrinkage strain, occurring upon UV curing and aging, leads to non-uniform dimensional changes that can compromise the part’s final geometry. This study investigates the deformation of green parts during the stereolithography process.
Dylan Vallet +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
A Simple Analytic Method to Model and Detect Non-Uniform Air-Gaps in Synchronous Generators
Iranian Journal of Electrical and Electronic Engineering, 2010 The air-gap of electrical machines may become non-uniform due to low accuracy of the manufacturing machinery, in assembling processes, or by aging. Detection and monitoring of this phenomenon is very important and of interest.
A. Damaki Aliabad +2 more
doaj
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Research on High-Quality Development of Corporate Pensions from a Multi-Pillar Pension Perspective [PDF]
SHS Web of ConferencesThe corporate pension system is an integral component of the multi-pillar retirement framework. It is a retirement security system jointly participated in by employers and employees and represents a collective form of employee personal accounts and ...
Wang Weiye
doaj +1 more source
Aging is a process that should be celebrated every day
, 2012 Jan. 12, 2012-; "... A blog-like publication that connects interest Ohioans to news and information about issues affecting older Ohioans and the people who care for and serve them."; Not published Feb.-Nov. 2013.; Issue for Jan.
Matura, Pamela K. +1 more
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Batteries, 2017 The number of Stationary Battery Systems (SBS) connected to various power distribution networks across the world has increased drastically. The increase in the integration of renewable energy sources is one of the major contributors to the increase in ...
Nandha Kumar Kandasamy +4 more
doaj +1 more source
Nanomaterials, 2020 The fracture behavior and crack sensing of mode-I joints with carbon nanotube (CNT)-reinforced adhesive films were explored in this paper under hydrothermal aging conditions.
Xoan F. Sánchez-Romate +3 more
doaj +1 more source