Results 61 to 70 of about 88,367 (250)

Thermal engineering of ZnMgO as electron transport layers for high-reliability quantum dot light-emitting diodes

Nano Research
The commercialization of self-emissive quantum dot light-emitting diode (QLED) faces several critical challenges. A primary obstacle is the reliance on acid-induced positive aging protocols using UV-curable resin to enhance device efficiency and ...
Xiang-Bing Fan, Donghui Yu, Di Zhang, Xu Yuan, Shan Yu, Xiaofei Zhao, Haoze Yang, Haoyu Yang, Dong Li, Zhuo Chen, Yanzhao Li   +10 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Influence of Relative Humidity and Aging on Morphology and Chemical Composition on Biomass Burning Particle

Aerosol and Air Quality Research
Agricultural waste burning is a major source of fine particulate matter (FPM), which remains in long-term suspension in the atmosphere during the aging processes.
Titinan Utavong, Thunyapat Thongyen, Surat Bualert, Parkpoom Choomanee, Saranarat Kongkeaw, Tanawan Rattanapotanan, Jitlada Phupijit, Suteekan Maneejantra, Nitchakarn Changplaiy   +8 more
doaj   +1 more source

Characterization of long-term field aging: differential impacts on rheological, chemical, and morphological properties of binders across the lanes of flexible pavement

International Journal of Transportation Science and Technology
Field aging is a complicated process wherein the binder ages inevitably due to the synergic effects of temperature, humidity, pressure, ultraviolet (UV) rays, and oxidation that occur in the field, and has a significant impact on the service life of ...
S. Tejeshwini, K.H. Mamatha, S.V. Dinesh
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Potential of strain-integrated gas infusion (SIGI) casting on post-heat treatment kinetics of AZ91 magnesium alloy

Journal of Magnesium and Alloys
Heat treatments play a crucial role in enhancing the mechanical properties of AZ91 Mg alloy by dissolving coarse phases during solution treatment and promoting precipitation during aging.
V. Tiwari, S.K. Panigrahi
doaj   +1 more source

Quantification of Damage Progression in a Thermally Aged Duplex Stainless Steel

Materials Research, 2002
Ferrite of austeno-ferritic stainless steels maintained for a long time at temperatures in the range of 270 °C to 400 °C is embrittled like the known 475 °C embrittlement of ferritic stainless steels.
A. Hazarabedian, B. Marini
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source