Results 61 to 70 of about 11,105,791 (289)

Aging connection (Columbus, Ohio : Online)

, 2006
Monthly; Electronic coverage as of May 22, 2007: Mar. 2006-; Description based on Mar. 2006; title from Web page (viewed on May 22, 2007).; Harvested from the web on 5/22/07June 2006, Ohio Leads Nation in Senior Services Levy Revenue. Department of Aging
Ohio. Dept. of Aging
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Thermal engineering of ZnMgO as electron transport layers for high-reliability quantum dot light-emitting diodes

Nano Research
The commercialization of self-emissive quantum dot light-emitting diode (QLED) faces several critical challenges. A primary obstacle is the reliance on acid-induced positive aging protocols using UV-curable resin to enhance device efficiency and ...
Xiang-Bing Fan, Donghui Yu, Di Zhang, Xu Yuan, Shan Yu, Xiaofei Zhao, Haoze Yang, Haoyu Yang, Dong Li, Zhuo Chen, Yanzhao Li   +10 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Influence of Relative Humidity and Aging on Morphology and Chemical Composition on Biomass Burning Particle

Aerosol and Air Quality Research
Agricultural waste burning is a major source of fine particulate matter (FPM), which remains in long-term suspension in the atmosphere during the aging processes.
Titinan Utavong, Thunyapat Thongyen, Surat Bualert, Parkpoom Choomanee, Saranarat Kongkeaw, Tanawan Rattanapotanan, Jitlada Phupijit, Suteekan Maneejantra, Nitchakarn Changplaiy   +8 more
doaj   +1 more source

Characterization of long-term field aging: differential impacts on rheological, chemical, and morphological properties of binders across the lanes of flexible pavement

International Journal of Transportation Science and Technology
Field aging is a complicated process wherein the binder ages inevitably due to the synergic effects of temperature, humidity, pressure, ultraviolet (UV) rays, and oxidation that occur in the field, and has a significant impact on the service life of ...
S. Tejeshwini, K.H. Mamatha, S.V. Dinesh
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Potential of strain-integrated gas infusion (SIGI) casting on post-heat treatment kinetics of AZ91 magnesium alloy

Journal of Magnesium and Alloys
Heat treatments play a crucial role in enhancing the mechanical properties of AZ91 Mg alloy by dissolving coarse phases during solution treatment and promoting precipitation during aging.
V. Tiwari, S.K. Panigrahi
doaj   +1 more source