Results 31 to 40 of about 88,367 (250)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

Anti-inflammatory and anti-aging activity of hydrogel with active ingredient Phyllantus emblica L. fruit nanosimplicia [PDF]

open access: yesJournal of Medicinal Plants, 2023
Background: Phyllantus emblica contains quite high levels of vitamin C as an antioxidant, premature aging and anti-inflammatory. Simplicia is formulated into a hydrogel because it has good dispersion power on the skin.
Masfria Masfria   +3 more
doaj  

Plankton response to global warming is characterized by non-uniform shifts in assemblage composition since the last ice age

open access: yesNature Ecology & Evolution, 2022
AbstractBiodiversity is expected to change in response to future global warming. However, it is difficult to predict how species will track the ongoing climate change. Here we use the fossil record of planktonic foraminifera to assess how biodiversity responded to climate change with a magnitude comparable to future anthropogenic warming.
Tonke Strack   +4 more
openaire   +2 more sources

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei   +17 more
wiley   +1 more source

Grading ring parameters optimization for 220 kV metal‐oxide arrester using 3D‐FEM method and bat algorithm

open access: yesIET Science, Measurement & Technology, 2021
Aging of metal oxide surge arresters is mainly affected by the high electric stress near the high voltage electrode. It has been observed that the distribution of voltage and electric field along an arrester is non‐uniform.
Nadjim Alti   +2 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen   +21 more
wiley   +1 more source

How Non-Uniform Temperatures Influence the Performance and Ageing of Lithium-Ion Batteries

open access: yes, 2021
Lithium-Ionen Batterien (LIB) finden aufgrund ihrer Vorteile hinsichtlich Energie- und Leistungsdichte sowie ihrer Zuverlässigkeit verbreitete An-wendung als elektrochemische Energiespeicher. Sie spielen im Rahmen des Klimawandels und der dadurch bedingten Energiewende eine zentrale Rolle in der Elektrifizierung der Mobilität.
openaire   +3 more sources

Survival by Race and Ethnicity in Children and Adolescents/Young Adults With Relapsed/Refractory Hodgkin Lymphoma: A Pooled Analysis of Children's Oncology Group Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Despite 5‐year survival rates of over 90% among children and adolescents/young adults (CAYAs) with classic Hodgkin lymphoma (cHL), 15%–20% relapse after frontline therapy. Prior analysis of frontline Children's Oncology Group (COG) clinical trials demonstrated that, despite similar rates of relapse, non‐Hispanic Black (NHB) and ...
Mallorie B. Heneghan   +14 more
wiley   +1 more source

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