Results 171 to 180 of about 78,820 (216)

Increased risk of nonalcoholic fatty liver disease in patients with thyroid cancer: a nationwide cohort study. [PDF]

BMC Cancer
Cho YB, Park KS.
europepmc   +1 more source

The 3xTg‐AD Mouse Model of Alzheimer's Disease Exhibits Lifelong Reductions in Circulating Choline Despite Adequate Dietary Intake, With Sex‐Specific Neuropathological and Behavioral Phenotypes

Aging Cell, Volume 25, Issue 1, January 2026.
This study found that 3xTg‐AD mice exhibited lifelong reductions in circulating choline. Female 3xTg‐AD mice showed greater AD‐like pathology, whereas males displayed higher mortality, impulsivity, and water‐seeking behavior. These sex‐specific differences suggest distinct metabolic and behavioral vulnerabilities contributing to AD progression in this ...
Jessica M. Judd, Faizan Mistry, Wendy Winslow, Savannah Tallino, Julie Turk, Ramon Velazquez   +5 more
wiley   +1 more source

Assessing Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Patients at a Tertiary Hospital, Addis Ababa, Ethiopia. [PDF]

J Diabetes Res
Berhe EA, Sema RA, Tesfaye YM, Berhane AA, Dawit M, Gebrehiwot EM, Yesuf SA.   +6 more
europepmc   +1 more source

Lipid Droplet‐Driven Ribosome Collisions Trigger ZAKα‐p38 Signaling to Accelerate Testicular Aging

Aging Cell, Volume 25, Issue 1, January 2026.
Aging‐ and obesity‐driven lipid droplet accumulation in Sertoli cells induces ROS‐mediated ribosome collisions, activating the ZAKα‐p38 pathway to accelerate testicular aging. Pharmacological ZAKα inhibition with Nilotinib rescues age‐related testicular dysfunction, identifying ribotoxic stress as a therapeutic target.
Yanghua Xu, Xiaoyan Shi, Yinghao Yin, Xiaoli Tan, Ningjing Ou, Xiaopeng Tang, Biao Liu, Hongshan Xie, Yuzhuo Chen, Zhitao Han, Jiarong Xu, Zitaiyu Li, Xiaoping Zheng, Hongji Hu, Wenjing Wang, Wanyi Xia, Hao Chen, Yuxin Tang, Liangyu Zhao   +18 more
wiley   +1 more source

Portal Vein Pulsatility Index as a Noninvasive Tool for Staging Nonalcoholic Fatty Liver Disease: A Case-Control Study. [PDF]

Cureus
Mohan S, Sakalecha AK, A R, Krishnan J, S N R.   +4 more
europepmc   +1 more source

Resting energy expenditure in adults with nonalcoholic fatty liver disease and type 2 diabetes mellitus: comparison between measured and predicted values. [PDF]

BMC Gastroenterol
Mansour A, Ebrahimi Mousavi S, Hemmati A, Hekmatdoost A, Qorbani M, Gerami H, Mirahmad M, Mohajeri-Tehrani MR, Baradaran F, Mirlohi SH, Sajjadi-Jazi SM.   +10 more
europepmc   +1 more source

Therapeutic Potential of Melatonin in Gastrointestinal Cancers: Molecular Mechanisms, Preclinical Evidence and Clinical Implications

Journal of Pineal Research, Volume 78, Issue 1, January 2026.
ABSTRACT Gastrointestinal (GI) cancers remain a leading cause of global morbidity and mortality, necessitating novel therapeutic strategies. Melatonin (MEL), an indoleamine with pleiotropic biological activities, has emerged as a promising adjuvant in oncology due to its antiproliferative, proapoptotic, and antioxidant properties.
Maciej Gonciarz, Benita Wiatrak, Iga Lombard, Łukasz Konecki, Joanna Sarbinowska   +4 more
wiley   +1 more source

Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications. [PDF]

Asia Pac J Clin Nutr
Zhang Z, Li S, Sun J.
europepmc   +1 more source

Beyond the Green Light: Evaluating the Uncertainties of Resmetirom for Non‐Cirrhotic Nonalcoholic Steatohepatitis Treatment

Health Science Reports, Volume 9, Issue 1, January 2026.
Hafiz Muhammad Moaaz Sajid, Fakiha Rahman, Abubakr Mahmoud   +2 more
wiley   +1 more source

Targeted Surgical Repair of a Symptomatic Hepatic Artery Aneurysm: Case Insights and Outcomes

Case Reports in Surgery, Volume 2026, Issue 1, 2026.
Introduction Hepatic artery aneurysms (HAAs) are rare but significant vascular lesions associated with high mortality due to rupture, particularly in symptomatic cases. This report highlights the clinical importance of timely intervention and presents a case of surgical management of a true HAA.
Alessandro Robaldo, Francesca Mariani, Alessandra Cristaudi, Giorgio Prouse, Pietro Majno-Hurst, Luca Giovannacci, Tulika Banerjee   +6 more
wiley   +1 more source