Results 11 to 20 of about 136,928 (265)
Microbiology Spectrum, 2019 ABSTRACT Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic bacteria such as Staphylococcus aureus , control the expression of genes encoding virulence factors or metabolic proteins.
Desgranges, E. +4 more
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The miR-183 Cluster: Biogenesis, Functions, and Cell Communication via Exosomes in Cancer
Cells, 2023 Cancer is one of the leading causes of human death. MicroRNAs have been found to be closely associated with cancer. The miR-183 cluster, comprising miR-183, miR-96, and miR-182, is transcribed as a polycistronic miRNA cluster. Importantly, in most cases,
Shuhui Li +6 more
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Cells, 2022 Cisplatin (CP), which is a conventional cancer chemotherapeutic drug, induces apoptosis by modulating a diverse array of gene regulatory mechanisms. However, cisplatin-mediated changes in the m6A methylome are unknown.
Azime Akçaöz Alasar +5 more
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Biology, 2023 Inter-tissue communication (ITC) is critical for maintaining the physiological functions of multiple tissues and is closely related to the onset and development of various complex diseases. Nevertheless, there is no well-organized data resource for known
Changxian Xiong +6 more
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Frontiers in Cell and Developmental Biology, 2021 Cisplatin is a well-known cancer chemotherapeutic agent but how extensively long non-coding RNA (lncRNA) expression is modulated by cisplatin is unknown. It is imperative to employ a comprehensive approach to obtain a better account of cisplatin-mediated
Dilek Cansu Gurer +7 more
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Noncoding RNA in Cholangiocarcinoma [PDF]
Seminars in Liver Disease, 2018 AbstractCholangiocarcinomas (CCAs) are tumors with a dismal prognosis. Early diagnosis is a key challenge because of the lack of specific symptoms, and the curability rate is low due to the difficulty in achieving a radical resection and the intrinsic chemoresistance of CCA cells.
Salati, Massimiliano, Braconi, Chiara
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Long noncoding RNA: noncoding and not coded [PDF]
Cell Death Discovery, 2017 Mammalian evolution exhibits extraordinary acceleration in phenotypic complexity while displaying genetic conservation. Indeed, protein-coding genes are 90% identical between mice and human, and the question arises what might be the mechanisms by which phenotypic complexity increases while the number of proteins does not?
Toiber, Debra +2 more
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Molecular Therapy: Nucleic Acids, 2021 Non-small cell lung cancer (NSCLC) is the most common form of cancer, resulting in cancer-related deaths worldwide. Exosomes, a subclass of extracellular vesicles, are produced and secreted from various types of cells, including cancer cells.
Jinbao Zhou +7 more
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Tanshinone Inhibits NSCLC by Downregulating AURKA Through Let-7a-5p
Frontiers in Genetics, 2020 Lung cancer is the most deadly malignancy in the last decade, accounting for about 1.6 million deaths every year globally. Tanshinone is the constituent of Salvia miltiorrhiza; it has been found that they influence tumorigenesis.
Xiaomin Liu +8 more
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Noncoding RNAs and Stroke [PDF]
The Neuroscientist, 2018 Over many years, extensive efforts have focused on the development and improvement of diagnostic and therapeutic strategies to reduce stroke-associated neurovascular damage, such as blood-brain barrier dysfunction, brain edema, parenchymal inflammation, and neural cell death.
Xuejing Zhang +2 more
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