Results 11 to 20 of about 137,421 (266)
Microbiology Spectrum, 2019 ABSTRACT Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic bacteria such as Staphylococcus aureus , control the expression of genes encoding virulence factors or metabolic proteins.
Desgranges, E. +4 more
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Noncoding RNA in Cholangiocarcinoma [PDF]
Seminars in Liver Disease, 2018 AbstractCholangiocarcinomas (CCAs) are tumors with a dismal prognosis. Early diagnosis is a key challenge because of the lack of specific symptoms, and the curability rate is low due to the difficulty in achieving a radical resection and the intrinsic chemoresistance of CCA cells.
Salati, Massimiliano, Braconi, Chiara
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Long noncoding RNA: noncoding and not coded [PDF]
Cell Death Discovery, 2017 Mammalian evolution exhibits extraordinary acceleration in phenotypic complexity while displaying genetic conservation. Indeed, protein-coding genes are 90% identical between mice and human, and the question arises what might be the mechanisms by which phenotypic complexity increases while the number of proteins does not?
Toiber, Debra +2 more
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Noncoding RNAs and Stroke [PDF]
The Neuroscientist, 2018 Over many years, extensive efforts have focused on the development and improvement of diagnostic and therapeutic strategies to reduce stroke-associated neurovascular damage, such as blood-brain barrier dysfunction, brain edema, parenchymal inflammation, and neural cell death.
Xuejing Zhang +2 more
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Noncoding RNAs in the Brain [PDF]
The Journal of Neuroscience, 2007 Cells transcribe thousands of RNAs that do not appear to encode proteins. The neuronal functions of these noncoding RNAs (ncRNAs) are for the most part not known, but specific ncRNAs have been shown to regulate dendritic spine development, neuronal fate specification and differentiation, and synaptic protein synthesis.
John S, Satterlee +6 more
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Noncoding RNAs and cancer [PDF]
Silence, 2011 The study of miRNAs and other noncoding RNAs has revolutionised our understanding of gene expression regulation during cancer development and progression, creating one of the fastest-growing research fields in cancer with realistic therapeutic potential.
Yogev, Ohad, Lagos, Dimitris
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Frontiers in Cell and Developmental Biology, 2022 Female reproductive cycle, also known as menstrual cycle or estrous cycle in primate or non-primate mammals, respectively, dominates the reproductive processes in non-pregnant state.
Yiran Zhou +14 more
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smORFunction: a tool for predicting functions of small open reading frames and microproteins
BMC Bioinformatics, 2020 Background Small open reading frame (smORF) is open reading frame with a length of less than 100 codons. Microproteins, translated from smORFs, have been found to participate in a variety of biological processes such as muscle formation and contraction ...
Xiangwen Ji, Chunmei Cui, Qinghua Cui
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MicroRNA-486-5p Suppresses Lung Cancer via Downregulating mTOR Signaling In Vitro and In Vivo
Frontiers in Oncology, 2021 Lung cancer is one of the central causes of tumor-related deaths globally, of which non-small cell lung cancer (NSCLC) takes up about 85%. As key regulators of various biological processes, microRNAs (miRNAs) have been verified as crucial factors in ...
Lei Ding +7 more
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, 2015 EBV expresses a number of viral noncoding RNAs (ncRNAs) during latent infection, many of which have known regulatory functions and can post-transcriptionally regulate viral and/or cellular gene expression. With recent advances in RNA sequencing technologies, the list of identified EBV ncRNAs continues to grow.
Rebecca L, Skalsky, Bryan R, Cullen
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