Results 21 to 30 of about 136,928 (265)
International Journal of Genomics, 2021 Diabetic foot ulcers are seriously endangering the physical and mental health of patients. Due to the long duration of inflammation, the treatment of nonhealing wounds in diabetes is one of the most prominent healthcare problems in the world. The nuclear
Xianyi Wang +3 more
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Screening and Comprehensive Analysis of Cancer-Associated tRNA-Derived Fragments
Frontiers in Genetics, 2022 tRNA-derived fragments (tRFs) constitute a novel class of small non-coding RNA cleaved from tRNAs. In recent years, researches have shown the regulatory roles of a few tRFs in cancers, illuminating a new direction for tRF-centric cancer researches ...
Yiran Zhou +5 more
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Cellular senescence: A potential mode of circular RNAs regulating prostate cancer
MedComm – Oncology, 2023 Cellular senescence is a state characterized by permanent cell cycle stoppage, which has long been viewed as a protective mechanism against neoplasia. However, accumulating evidence reveal that cellular senescence variously stimulates tumorigenesis and ...
Yunpeng Li +7 more
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A promising nucleic acid therapy drug: DNAzymes and its delivery system
Frontiers in Molecular Biosciences, 2023 Based on the development of nucleic acid therapeutic drugs, DNAzymes obtained through in vitro selection technology in 1994 are gradually being sought.
Lang Xiao +12 more
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Frontiers in Cell and Developmental Biology, 2022 Female reproductive cycle, also known as menstrual cycle or estrous cycle in primate or non-primate mammals, respectively, dominates the reproductive processes in non-pregnant state.
Yiran Zhou +14 more
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Noncoding RNAs and Atherosclerosis [PDF]
Current Atherosclerosis Reports, 2014 Noncoding RNAs (ncRNAs) represent a class of RNA molecules that typically do not code for proteins. Emerging data suggest that ncRNAs play an important role in several physiological and pathological conditions such as cancer and cardiovascular diseases, including atherosclerosis.
Binod, Aryal +2 more
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smORFunction: a tool for predicting functions of small open reading frames and microproteins
BMC Bioinformatics, 2020 Background Small open reading frame (smORF) is open reading frame with a length of less than 100 codons. Microproteins, translated from smORFs, have been found to participate in a variety of biological processes such as muscle formation and contraction ...
Xiangwen Ji, Chunmei Cui, Qinghua Cui
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MicroRNA-486-5p Suppresses Lung Cancer via Downregulating mTOR Signaling In Vitro and In Vivo
Frontiers in Oncology, 2021 Lung cancer is one of the central causes of tumor-related deaths globally, of which non-small cell lung cancer (NSCLC) takes up about 85%. As key regulators of various biological processes, microRNAs (miRNAs) have been verified as crucial factors in ...
Lei Ding +7 more
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Noncoding RNAs in the Brain [PDF]
The Journal of Neuroscience, 2007 Cells transcribe thousands of RNAs that do not appear to encode proteins. The neuronal functions of these noncoding RNAs (ncRNAs) are for the most part not known, but specific ncRNAs have been shown to regulate dendritic spine development, neuronal fate specification and differentiation, and synaptic protein synthesis.
John S, Satterlee +6 more
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Uirusu, 2009 Many lines of recent evidence indicate that non-coding RNAs including micro RNAs (miRNAs) and small interfering RNAs (siRNAs) play an important role in the control of gene expression in diverse cellular processes and in defense responses against molecular parasites such as viruses and transposons.
IWAKAWA, Hiro-oki, OKUNO, Testuro
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