Results 31 to 40 of about 136,928 (265)
The role of noncoding RNAs in the tumor microenvironment of hepatocellular carcinoma
Acta Biochimica et Biophysica Sinica, 2023 Hepatocellular carcinoma (HCC) is the leading fatal malignancy worldwide. The tumor microenvironment (TME) can affect the survival, proliferation, migration, and even dormancy of cancer cells.
Yang Qianqian +4 more
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, 2015 EBV expresses a number of viral noncoding RNAs (ncRNAs) during latent infection, many of which have known regulatory functions and can post-transcriptionally regulate viral and/or cellular gene expression. With recent advances in RNA sequencing technologies, the list of identified EBV ncRNAs continues to grow.
Rebecca L, Skalsky, Bryan R, Cullen
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Noncoding RNAs and cancer [PDF]
Silence, 2011 The study of miRNAs and other noncoding RNAs has revolutionised our understanding of gene expression regulation during cancer development and progression, creating one of the fastest-growing research fields in cancer with realistic therapeutic potential.
Yogev, Ohad, Lagos, Dimitris
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Noncoding RNAs in neurodegeneration [PDF]
Nature Reviews Neuroscience, 2017 The emerging complexity of the transcriptional landscape poses great challenges to our conventional preconceptions of how the genome regulates brain function and dysfunction. Non-protein-coding RNAs (ncRNAs) confer a high level of intricate and dynamic regulation of various molecular processes in the CNS and they have been implicated in ...
Salta, E, De Strooper, B
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A new synthetic protocol for coumarin amino acid
Beilstein Journal of Organic Chemistry, 2013 The hydrochloride of the racemic amino acid (2-(7-hydroxycoumarin-4-yl)ethyl)glycine, which can serve as a fluorescent probe in proteins, and two halogen derivatives of it, were synthesized by using a new synthetic protocol in five steps.
Xinyi Xu, Xiaosong Hu, Jiangyun Wang
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A comparative analysis of lncRNAs in prostate cancer exosomes and their parental cell lines
Genomics Data, 2016 Prostate cancer is the second leading cancer in men world-wide. Due to its heterogeneous nature, a considerable amount of research effort has been dedicated in identifying effective clinical biomarkers with a focus on proteins, messenger RNA and ...
Alireza Ahadi +3 more
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p53/MicroRNA-34 axis in cancer and beyond
Heliyon, 2023 Cancer is serious endangers human life. After a long period of research and accumulation, people's understanding of cancer and the corresponding treatment methods are constantly developing. p53 is an important tumor suppressor gene.
Wei Pan +4 more
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Distinct MicroRNA Subcellular Size and Expression Patterns in Human Cancer Cells
International Journal of Cell Biology, 2012 Introduction. Small noncoding RNAs have important regulatory functions in different cell pathways. It is believed that most of them mainly play role in gene post-transcriptional regulation in the cytoplasm.
Beibei Chen +5 more
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Microprocessor Activity Controls Differential miRNA Biogenesis In Vivo
Cell Reports, 2014 In miRNA biogenesis, pri-miRNA transcripts are converted into pre-miRNA hairpins. The in vivo properties of this process remain enigmatic. Here, we determine in vivo transcriptome-wide pri-miRNA processing using next-generation sequencing of chromatin ...
Thomas Conrad +3 more
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Noncoding RNAs in Cancer Medicine [PDF]
BioMed Research International, 2006 Several signalling proteins involved in cell growth and differentiation represent attractive candidate targets for cancer diagnosis and/or therapy since they can act as oncogenes. Because of their high specificity and low immunogeneicity, using artificial small noncoding RNA (ncRNAs) as therapeutics has recently become a highly promising and rapidly ...
Cerchia L, de Franciscis V
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