Results 101 to 110 of about 243,847 (257)
Advanced Science, EarlyView.A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao +34 more
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Noncoding RNAs Regulating Differentiation and Cancer
, 2017 I will present novel long noncoding RNAs that we have identified because of their roles in skeletal muscle differentiation (H19 and MUNC) and in the progression of cancers (DRAIC).
Dutta, MD, PhD, Anindya
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Noncoding RNA in the Transcriptional Landscape of Human Neural Progenitor Cell Differentiation
Frontiers in Neuroscience, 2015 Increasing evidence suggests that noncoding RNAs play key roles in cellular processes, particularly in the brain. The present study used RNA sequencing to identify the transcriptional landscape of two human neural progenitor cell lines, SK-N-SH and ...
Patrick eHecht +6 more
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Noncoding RNAs database (ncRNAdb
, 2007 The noncoding RNA database (ncRNAdb) was crea-ted as a source of information on RNA molecules, which do not possess protein-coding capacity. It is now widely accepted that, in addition to constitu-tively expressed, housekeeping or infrastructural RNAs ...
Maciej Szymanski +2 more
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Long Noncoding RNAs: Central to Nervous System Development
, 2016 The development of the central nervous system (CNS) is a complex orchestration of stem cells, transcription factors, growth/differentiation factors, and epigenetic control.
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Advanced Science, EarlyView.Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou +13 more
wiley +1 more source
Exosomal noncoding RNA: A potential therapy for retinal vascular diseases
Molecular Therapy: Nucleic AcidsExosomes are extracellular vesicles that can contain DNA, RNA, proteins, and metabolites. They are secreted by cells and play a regulatory role in various biological responses by mediating cell-to-cell communication. Moreover, exosomes are of interest in
Jong-Ik Heo, Juhee Ryu
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Noncoding RNAs as potential biomarkers to predict the outcome in pancreatic cancer
, 2015 Kaizhou Jin,1–3,* Guopei Luo,1–3,* Zhiwen Xiao,1–3 Zuqiang Liu,1–3 Chen Liu,1–3 Shunrong Ji,1–3 Jin Xu,1–3 Liang Liu,1–3 Jiang Long,1–3 Quanxing Ni,1–3 Xianjun Yu1–3 1Department of ...
Ji S +10 more
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Annals of Gastroenterological Surgery, EarlyView.Gastric cancer metastasis should be considered according to its anatomical route, because lymphatic, peritoneal, and hematogenous dissemination involve partly distinct molecular mechanisms. This review summarizes metastasis pattern‐associated and pattern‐specific molecules identified using surgical specimens, evaluates their evidence and translational ...
Mitsuro Kanda
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American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Arthrogryposis multiplex congenita (AMC) is a group of rare congenital conditions, characterized by multiple joint contractures but may involve any body system including central nervous system. AMC is etiologically heterogeneous, with over 400 genetic and many non‐genetic causes implicated in its prenatal development.
Shahrzad Nematollahi +20 more
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