Results 161 to 170 of about 243,847 (257)

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

Unveiling the Silent Regulators: Noncoding RNAs in Parasitic Disease Diagnosis and Therapy. [PDF]

J Parasitol Res
Loku Gamage N, Ranasinghe K.
europepmc   +1 more source

Genomics and epigenomics of tissue repair: Implications for personalized medicine

Precision Medical Sciences, EarlyView.
Genomic and epigenomic mechanisms govern tissue repair and regeneration through dynamic regulation of inflammation, cell fate, and extracellular matrix remodeling. The integration of multi‐omics, artificial intelligence, and precision regenerative therapies enables biomarker‐driven, personalized approaches to enhance healing and minimize fibrosis ...
Jharna Medhi, Chandrashekar Thalluri, Sarad Pawar Naik Bukke, Piyali Dey, Mallikarjun Vasam, Ananda Kumar Chettupalli, Swetha Kumari Koduru, Gali Avinash Kumar   +7 more
wiley   +1 more source

Characterization of long noncoding RNAs, microRNAs, and piwiRNAs in reef-building corals. [PDF]

Environ Epigenet
Ashey J, Rodriguez-Casariego JA, Durkin KM, Bengtsson Z, White SJ, Huffmyer AS, Becker DM, Eirin-Lopez JM, Putnam HM, Roberts SB.   +9 more
europepmc   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

Pest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano, Carmen Scieuzo, Rosanna Salvia, Riccardo Moretti, Flora Cozzolino, Maria Monti, Heiko Vogel, Patrizia Falabella   +7 more
wiley   +1 more source

Expanding Transposase Technology to Regulatory Noncoding RNAs for Stable Expression in CHO Cells. [PDF]

Biotechnol J
Lochmueller S, Weiss L, Otte K.
europepmc   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Long Noncoding RNAs (lncRNAs) as Biomarkers of Prognosis in TNBC and Non-TNBC Breast Cancer Patients. [PDF]

Int J Mol Sci
Acencio ML, Wang X, Mangone FRR, Carraro DM, Llera AS, Abdelhay ESFW, Artagaveytia N, Daneri-Navarro A, Reis EM, Sanches L, Chammas R, Podhajcer OL, Velazquez C, Nagai MA.   +13 more
europepmc   +1 more source

Inhibition of Type 2 Transglutaminase significantly alters long noncoding RNAs expression in triplenegative breast cancer cell line.

Type 2 Transglutaminase (TG2) is an ubiquitously expressed enzyme involved in various physiological and pathological processes, strongly linked to cancer.
A. Pignatelli, A. Terrazzan, G. Salvi, Nicoletta Bianchi, J. W. Keillor, P. Ancona, F. P. Carbone, C. Taccioli, S. Volinia   +8 more
core  

Multiscale Effects of Environmentally Relevant Mixtures Containing Two Estrogenic Endocrine Disruptors, Chlordecone and Propylparaben, in Hydra vulgaris Pallas, 1766

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates the chronic effects of chlordecone (CLD) and propylparaben (PP), two pro‐estrogenic endocrine disruptors, on Hydra vulgaris Pallas, 1766 using a multiscale approach over a 14‐day exposure period. Environmentally relevant concentrations of CLD (0.5, 5, 20 μg L−1) and PP (0.01, 0.05, 0.40 μg L−1) were tested individually ...
Magali Domallain, Romain Colpaert, Xavier Moreau, Laetitia De Jong, Karim Benbrahim, Raphael Coatmeur, Valérie Pique, Maxime Robin, Pierre‐Henri Villard   +8 more
wiley   +1 more source