Results 181 to 190 of about 243,847 (257)

Overexpression of a subset of long intergenic noncoding RNAs in uterine serous carcinoma predicts poor prognosis. [PDF]

Medicine (Baltimore)
Zhang Y, Huang QY, Qin X, Ma LL, Ye H.
europepmc   +1 more source

MitoOmicsDB: A Web Platform for Mitochondrial Genome Curation and Gene Order Analysis Across Metazoa

Integrative Zoology, EarlyView.
MitoOmicsDB is a curated web platform for standardizing, searching, visualizing, and comparing mitochondrial genomes across Metazoa. By integrating automated annotation normalization with manual curation, the platform provides accession‐linked data for comparative studies of mitochondrial gene content and gene order.
Haihe Shi, Renzeng Du, Gengyun Niu, Meicai Wei   +3 more
wiley   +1 more source

Diagnostic accuracy of circulating long noncoding RNAs in hepatocellular carcinoma: a systematic review and meta-analysis. [PDF]

BMC Gastroenterol
Babajani N, Saeedian B, Shirmard FO, Pourfaraji SM, Jodeiri F, Delavari A, Taheri E.   +6 more
europepmc   +1 more source

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Noncoding RNAs as Targets of Acute Kidney Injury Therapy: Ready for Primetime? [PDF]

Kidney360
Liu Z, Fu Y, Cai J, Chen G, Dong Z.
europepmc   +1 more source

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

British Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka, Georgios Sivvas, Evangelia Papadimitriou, Constantinos M. Mikelis   +3 more
wiley   +1 more source

Long non‐coding RNAs at the crossroads of inflammation, cancer and angiogenesis: Molecular mechanisms and their potential as therapeutic targets

British Journal of Pharmacology, EarlyView.
Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff, Pamela Calle‐Mendoza, Maria Hatziapostolou, Christos Polytarchou   +3 more
wiley   +1 more source

Assessing the contributions of noncoding RNAs in acute myeloid leukemia. [PDF]

Blood Neoplasia
Zakutansky PM, Boucher AC, Crispino JD.
europepmc   +1 more source

New Treatment Strategy and Future Research Direction for BRAF‐Mutated Cancer

Cancer Science, EarlyView.
Treatment with BRAF inhibitor plus MEK inhibitor is currently used in BRAF‐mutated various malignancies except colorectal cancer, and treatments with BRAF and/or MEK inhibitors and anti‐EGFR antibody are used in BRAF‐mutated colorectal cancer. Despite recent advances in BRAF‐targeted therapies, their efficacy is still limited.
Masanobu Takahashi, Sakura Hiraide Taniguchi, Yuya Yoshida   +2 more
wiley   +1 more source

Noncoding RNAs, Vital Players in Breast Cancer Metastasis. [PDF]

Breast Cancer (Dove Med Press)
Kang Y, Wang X, Liu Y, Cao J, Lin J, Qiao G.   +5 more
europepmc   +1 more source