Results 51 to 60 of about 243,847 (257)
Noncoding RNAs link metabolic reprogramming to immune microenvironment in cancers
Journal of Hematology & Oncology, 2021 Altered metabolic patterns in tumor cells not only meet their own growth requirements but also shape an immunosuppressive microenvironment through multiple mechanisms.
Yiyin Zhang +10 more
doaj +1 more source
Potential Regulatory Roles of MicroRNAs and Long Noncoding RNAs in Anticancer Therapies
Molecular Therapy: Nucleic Acids, 2018 MicroRNAs and long noncoding RNAs have long been investigated due to their roles as diagnostic and prognostic biomarkers of cancers and regulators of tumorigenesis, and the potential regulatory roles of these molecules in anticancer therapies are ...
Mengyan Xie +6 more
doaj +1 more source
Small RNAs Asserting Big Roles in Mycobacteria
Non-Coding RNA, 2021 Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb), with 10.4 million new cases per year reported in the human population.
Fatma S. Coskun +2 more
doaj +1 more source
Andrea Ventura: Decrypting noncoding RNAs
, 2017 Ventura explores the biological functions of noncoding RNAs in cancer and development.
Melina Casadio
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Cis-encoded noncoding antisense RNAs in streptococci and other low GC Gram (+) bacterial pathogens.
Frontiers in Genetics, 2015 Due to recent advances of bioinformatics and high throughput sequencing technology, discovery of regulatory noncoding RNAs in bacteria has been increased to a great extent.
Kyu Hong eCho, Jeong-Ho eKim
doaj +1 more source
TREAT: Therapeutic RNAs exploration inspired by artificial intelligence technology
Computational and Structural Biotechnology Journal, 2022 Recent advances in RNA engineering have enabled the development of RNA-based therapeutics for a broad spectrum of applications. Developing RNA therapeutics start with targeted RNA screening and move to the drug design and optimization.
Yufan Luo +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source