Results 71 to 80 of about 1,040,182 (211)

Nonesterified Fatty Acids and Hepatic Glucose Metabolism in the Conscious Dog [PDF]

Diabetes, 2004
We used tracer and arteriovenous difference techniques in conscious dogs to determine the effect of nonesterified fatty acids (NEFAs) on net hepatic glucose uptake (NHGU). The protocol included equilibration ([3-3H]glucose), basal, and two experimental periods (−120 to −30, −30 to 0, 0–120 [period 1], and 120–240 min [period 2], respectively).
Mary Courtney, Moore, Shosuke, Satake, Margaret, Lautz, Scott A, Soleimanpour, Doss W, Neal, Marta, Smith, Alan D, Cherrington   +6 more
openaire   +2 more sources

Estrogen Receptor Beta Activation Coordinates Liver Lipid Remodeling and Metabolic Fluxes, Preventing Lipotoxicity

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha, Eloisa Vilas‐Boas, Camille C. Caldeira da Silva, Everton L. Vogt, Marcos Yoshinaga, Mariana Pacheco Teixeira de Carvalho, Maiara I. C. Queiroz, Tiago Eugênio Oliveira da Silva, Sayuri Miyamoto, Alicia J. Kowaltowski   +9 more
wiley   +1 more source

Omega 3 fatty acids and cognitive health in older people. [PDF]

, 2012
Oily fish and other sources of long-chain n-3 polyunsaturated fatty acids (n-3 LCPs) have been proposed as protective against dementia and age related cognitive impairment.
Dangour, Alan, Uauy, Ricardo, Dangour, Alan D, Andreeva, Valentina, Andreeva, Valentina A, Sydenham, Emma   +5 more
core   +1 more source

Food, Fatty Acids and Antioxidants Intake and their Associations with Atopic disease in Adults [PDF]

, 2011
It was hypothesized that high fat consumption, specifically from polyunsaturated fatty acids, may be positively related to atopic disease prevalence.
Trak-Fellermeier, María Angélica
core   +1 more source

Plasma Levels of Free Fatty Acids in Women with Gestational Diabetes and Its Intrinsic and Extrinsic Determinants: Systematic Review and Meta-Analysis

Journal of Diabetes Research, 2019
Background. Free fatty acids, also known as nonesterified fatty acids, are proinflammatory molecules that induce insulin resistance in nonpregnant individuals.
Jose Rafael Villafan-Bernal, Mariana Acevedo-Alba, Rodrigo Reyes-Pavon, Guillermo Andres Diaz-Parra, Diana Lucia Lip-Sosa, Hilda Imelda Vazquez-Delfin, Martha Hernandez-Muñoz, Daniel Ely Bravo-Aguirre, Francesc Figueras, Raigam Jafet Martinez-Portilla   +9 more
doaj   +1 more source

Efficient and specific analysis of red blood cell glycerophospholipid fatty acid composition. [PDF]

, 2012
Red blood cell (RBC) n-3 fatty acid status is related to various health outcomes. Accepted biological markers for the fatty acid status determination are RBC phospholipids, phosphatidylcholine, and phosphatidyletholamine.
Hans Demmelmair, Klingler, Mario, Klem, Sabrina, Demmelmair Hans, Koletzko Berthold, Sabrina Klem, Berthold Koletzko, Klem Sabrina, Koletzko, Berthold, Mario Klingler, Klingler Mario, Demmelmair, Hans   +11 more
core   +2 more sources

Effects of fatty acids on inflammatory markers studied in vivo and in vitro

, 2008
Inflammation involves interactions amongst many different cell types as a defense mechanism of the body. Inflammation is also involved in cardiovascular disease (CVD).
Mohd Yusof, Hayati
core   +1 more source

Disturbed bovine mitochondrial lipid metabolism: a review

Veterinary Quarterly, 2017
In mammals, excess energy is stored primarily as triglycerides, which are mobilized when energy demands arise and cannot be covered by feed intake. This review mainly focuses on the role of long chain fatty acids in disturbed energy metabolism of the ...
J. H. (Han) van der Kolk, J. J. Gross, V. Gerber, R. M. Bruckmaier   +3 more
doaj   +1 more source

One-step rapid extractive methylation of plasma nonesterified fatty acids for gas chromatographic analysis.

Journal of Lipid Research, 1989
The present report describes a one-step method for the derivatization and extraction of nonesterified fatty acids in plasma with subsequent analysis by conventional capillary gas-liquid chromatography or gas-liquid chromatography-mass spectrometry.
C R Pace-Asciak
doaj   +1 more source

Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 8, August 2026.
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei, Xiyue Xiong, Lu Zhang, Jian Zhang, Lawrence W. C. Chan, Hong Jiang, Qingqing Xiong, Changtao Hu, Jie Chen, Sijun Yang   +9 more
wiley   +1 more source