Results 161 to 170 of about 627,327 (211)

Enzymatic Synthesis of a Polyketide/Nonribosomal Peptide Hybrid Antibiotic, Salivabactin. [PDF]

Biochemistry
Gu D, Zhai R, Daymo B, Xie Y, Luo C, Zhang W.   +5 more
europepmc   +1 more source

Chalkophomycin Biosynthesis Revealing Unique Enzyme Architecture for a Hybrid Nonribosomal Peptide Synthetase and Polyketide Synthase. [PDF]

Molecules
Yang L, Yi L, Yi L, Gong B, Chen L, Li M, Zhu X, Duan Y, Huang Y.   +8 more
europepmc   +1 more source

Nonribosomal Peptide Synthetase Specific Genome Amplification Using Rolling Circle Amplification for Targeted Gene Sequencing. [PDF]

Int J Mol Sci
Okamura Y, Suemitsu M, Ishikawa T, Takahashi H.   +3 more
europepmc   +1 more source

Structural, biochemical and bioinformatic analyses of nonribosomal peptide synthetase adenylation domains.

Nat Prod Rep
Heard SC, Winter JM.
europepmc   +1 more source

Exploring the substrate stereoselectivity and catalytic mechanism of nonribosomal peptide macrocyclization in surugamides biosynthesis. [PDF]

iScience
Du Z, Ma Y, Shen Y, Jiang X, Zhou Y, Shi T.   +5 more
europepmc   +1 more source

<i>FONPS6</i>, a Nonribosomal Peptide Synthetase, Plays a Crucial Role in Achieving the Full Virulence Potential of the Vascular Wilt Pathogen <i>Fusarium oxysporum</i> f. sp. <i>Niveum</i>. [PDF]

Life (Basel)
Li J, Gao Y, Li B, Zhang L, Fang Y, Zou H, Ye X.   +6 more
europepmc   +1 more source

Reprogramming Nonribosomal Peptide Synthesis

, 2018
openaire   +2 more sources

Correction to: Characterization and catalytic investigation of fungal single-module nonribosomal peptide synthetase in terpene-amino acid meroterpenoid biosynthesis. [PDF]

J Ind Microbiol Biotechnol
europepmc   +1 more source

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Nonribosomal Peptide Synthesis—Principles and Prospects

Angewandte Chemie - International Edition, 2017
Abstract Nonribosomal peptide synthetases (NRPSs) are large multienzyme machineries that assemble numerous peptides with large structural and functional diversity. These peptides include more than 20 marketed drugs, such as antibacterials (penicillin, vancomycin), antitumor compounds (bleomycin), and immunosuppressants (cyclosporine).
Roderich D. Süssmuth, Andi Mainz
exaly   +3 more sources

Engineering the biosynthesis of fungal nonribosomal peptides

Natural Product Reports, 2023
Fungal nonribosomal peptides (NRPs) and the related polyketide–nonribosomal peptide hybrid products (PK–NRPs) are a prolific source of bioactive compounds, some of which have been developed into essential drugs.
Zhang, Liwen, Wang, Chen, Chen, Kang, Zhong, Weimao, Xu, Yuquan, Molnár, István   +6 more
openaire   +3 more sources