Results 81 to 90 of about 8,679 (178)

Plastic Diets Drive Microbiome and Metabolic Reprogramming in Wax Moth Larvae (Achroia grisella)

Archives of Insect Biochemistry and Physiology, Volume 122, Issue 3, July 2026.
Wax moth larvae (Achroia grisella) can consume LDPE and PLA, triggering polymer‐specific restructuring of the gut microbiome and host metabolism. LDPE feeding enriches Bacillus spp. and is associated with shifts in carbohydrate and amino‐acid pathways consistent with hydrocarbon processing, whereas PLA feeding enriches Enterococcus spp.
Rohan Shah, Anna Marcora, Angela Ruffell, Georgia M. Sinclair, Inka Vanwonterghem, Andrew Bissett, Andrew Hulthen, Gene Wijffels, Cate Paull, David J. Beale   +9 more
wiley   +1 more source

Mining the Yucatan Coastal Microbiome for the Identification of Non-Ribosomal Peptides Synthetase (NRPS) Genes

Toxins, 2020
Prokaryotes represent a source of both biotechnological and pharmaceutical molecules of importance, such as nonribosomal peptides (NRPs). NRPs are secondary metabolites which their synthesis is independent of ribosomes.
Mario Alberto Martínez-Núñez, Zuemy Rodríguez-Escamilla   +1 more
doaj   +1 more source

Genomic and Functional Characterization of Sunflower Endophytes Reveals Mechanisms of Drought Tolerance and Growth Promotion

Plant Direct, Volume 10, Issue 7, July 2026.
ABSTRACT Drought severely limits sunflower (Helianthus annuus L.) productivity, necessitating sustainable microbial strategies to enhance plant resilience. Endophytic bacteria modulate plant stress responses through diverse plant growth‐promoting (PGP) traits.
Muritala Muhammed, Ayansina Segun Ayangbenro, Olubukola Oluranti Babalola   +2 more
wiley   +1 more source

Virulence, Host-Selective Toxin Production, and Development of Three Cochliobolus Phytopathogens Lacking the Sfp-Type 4′-Phosphopantetheinyl Transferase Ppt1

Molecular Plant-Microbe Interactions, 2015
The Sfp-type 4′-phosphopantetheinyl transferase Ppt1 is required for activation of nonribosomal peptide synthetases, including α-aminoadipate reductase (AAR) for lysine biosynthesis and polyketide synthases, enzymes that biosynthesize peptide and ...
Nur Ain Izzati Mohd Zainudin, Bradford Condon, Lieselotte De Bruyne, Christof Van Poucke, Qing Bi, Wei Li, Monica Höfte, B. Gillian Turgeon   +7 more
doaj   +1 more source

Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains

Current Research in Structural Biology, 2020
The recently discovered antibiotic teixobactin is produced by uncultured soil bacteria. The antibiotic inhibits cell wall synthesis of Gram-positive bacteria by binding to precursors of cell wall building blocks, and therefore it is thought to be less ...
Kemin Tan, Min Zhou, Robert P. Jedrzejczak, Ruiying Wu, Raul A. Higuera, Dominika Borek, Gyorgy Babnigg, Andrzej Joachimiak   +7 more
doaj   +1 more source

Crystal Structure and Conformational Dynamics of N─N Bond‐Forming Piperazate Synthase

ChemBioChem, Volume 27, Issue 12, 26 June 2026.
Piperazate synthases (PZSs) catalyze the key N─N bond formation in the biosynthesis of the rare amino acid piperazic acid. X‐ray crystal structures of apo‐ and holo‐SbPZS show a dimeric enzyme with two heme‐containing active sites, where histidine residues coordinate the iron centers.
Nikita Pal, Simon Schröder, Amit Singh Sahrawat, Christian C. Gruber, Martin A. Hayes, Bastian Daniel, Sandy Schmidt, Karl Gruber   +7 more
wiley   +1 more source

Aspergillus hancockii sp. nov., a biosynthetically talented fungus endemic to southeastern Australian soils.

PLoS ONE, 2017
Aspergillus hancockii sp. nov., classified in Aspergillus subgenus Circumdati section Flavi, was originally isolated from soil in peanut fields near Kumbia, in the South Burnett region of southeast Queensland, Australia, and has since been found ...
John I Pitt, Lene Lange, Alastair E Lacey, Daniel Vuong, David J Midgley, Paul Greenfield, Mark I Bradbury, Ernest Lacey, Peter K Busk, Bo Pilgaard, Yit-Heng Chooi, Andrew M Piggott   +11 more
doaj   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

Chemistry – A European Journal, Volume 32, Issue 24, 23 June 2026.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami, Hikari Ozawa, Sohei Ito   +2 more
wiley   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

Angewandte Chemie, Volume 138, Issue 26, 22 June 2026.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +1 more source

Draft genome sequence of a human-associated isolate of Haloferax alexandrinus strain Arc-hr, an extremely halophilic archaea

New Microbes and New Infections, 2017
We report the draft genome sequence of Haloferax alexandrinus strain Arc-hr (CSUR P798), isolated from the human gut of a 10-year-old Amazonian individual. Its 3 893 626 bp genome exhibits a 66.00% GC content.
S. Khelaifia, A. Caputo, F. Djossou, D. Raoult   +3 more
doaj   +1 more source