Results 141 to 150 of about 17,359 (221)

Identification and characterisation of novel involved in the nonsense-mediated mRNA decay (NMD) pathway

, 2016
Nonsense mediated mRNA decay (NMD) is a surveillance mechanism that targets transcripts containing premature stop codons (PTCs) for degradation, and that also regulates up to 10% of the whole transcriptome. During the course of my PhD I set out to identify novel NMD factors by performing a genome-wide RNA interference (RNAi) screen in a transgenic ...
openaire   +1 more source

Study of the nonsense-mediated decay (NMD) mechanism in the human \03B1-globin mRNA

, 2009
Fundação para a Ciência e Tecnologia (FCT), (POCI/BIA-BCM/59140/2004 e POCI/SAU-MMO/57573/2004), Programa de Financiamento Plurianual do Centro de Investigação em Genética Molecular Humana (CIGMH); SFRH/BD/14273/2003.
openaire   +1 more source

SMG6's PIN (PilT N-Terminus) Domain Is Required for Nonsense-Mediated mRNA Decay (NMD) <i>In Vivo</i>. [PDF]

Cells
Chai B, Tan X, Li Y, Chen C, Ma X, Li T.
europepmc   +1 more source

The nonsense-mediated mRNA decay factor Upf3 negatively regulates bulk autophagy progression in <i>Saccharomyces cerevisiae</i>. [PDF]

Autophagy Rep
Tasmi TA, Solomon E, Avogo EW, Badenahalli Narasimhaiah S, Delorme-Axford E.   +4 more
europepmc   +1 more source

Anticodon-edited tRNA enables translational readthrough of COL4A5 premature termination codons. [PDF]

PLoS One
Omachi K, Porter JJ, Lueck JD, Miner JH.
europepmc   +1 more source

A novel heterozygous pathogenic variation in the <i>MECP2</i> gene causing typical Rett syndrome: a case report. [PDF]

Transl Pediatr
Zheng Y, Yang Y, He L, Chen H, Wang D, Chen Y.   +5 more
europepmc   +1 more source

A Translational Roadmap for Neurological Nonsense Mutation Disorders. [PDF]

Int J Mol Sci
Li J, Zhu Z, Xu S.
europepmc   +1 more source

Nonsense-mediated decay controls a negative feedback loop in innate immune sensing. [PDF]

Proc Natl Acad Sci U S A
Boudreault S, Rivera-Lopez Y, Ferretti MB, Tracey MA, Bonner J, Jacobs BL, Lynch KW.   +6 more
europepmc   +1 more source

Variant identification and genotyping strategy for the <i>smg-1(r861)</i> allele in <i>Caenorhabditis elegans</i>. [PDF]

MicroPubl Biol
Zoberman M, Calarco JA.
europepmc   +1 more source

Plant P-bodies in post-transcriptional control: Composition, dynamics, and context-dependent roles. [PDF]

Plant Commun
Matinahmadi A, Zayani Z, Majewska K, Smoliński DJ.   +3 more
europepmc   +1 more source