Results 151 to 160 of about 17,359 (221)

Nonsense-mediated mRNA decay orchestrates neuronal migration and cortical lamination while modulating Reelin and ciliary gene regulatory networks. [PDF]

Cell Rep
Lin L, Kubota N, Lam YL, Song MM, Zhang M, Zheng S.   +5 more
europepmc   +1 more source

Identification of inhibitors of nonsense-mediated mRNA decay (NMD) and use as a therapeutic approach for some genetic diseases

, 2011
Le NMD (nonsense-mediated mRNA decay) est un mécanisme qui reconnaît et dégrade les ARNm portant un codon stop prématuré afin d’empêcher la synthèse de protéines tronquées qui pourraient avoir des effets néfastes pour la cellule ou tout simplement être non fonctionnelles.
openaire   +1 more source

Nonsense-mediated mRNA decay safeguards telomeres in pluripotent stem cells. [PDF]

Nat Cell Biol
Markiewicz-Potoczny M, Lee SY, Chatterjee S, Mabin JW, Zinsser A, Sandhu R, Tricola G, Hogg JR, Lazzerini Denchi E.   +8 more
europepmc   +1 more source

Transcripts expressed using a bicistronic vector pIREShyg2 are sensitized to nonsense-mediated mRNA decay [PDF]

, 2010
Yayoi Shikama, Huiyuan Hu, Makiko Ohno, Isao Matsuoka, Tsutomu Shichishima, Junko Kimura   +5 more
core   +1 more source

Mechanistic insights into coordinated var transcriptional switching in malaria parasites. [PDF]

EMBO J
Visone JE, Florini F, Hadjimichael E, Patel V, Deitsch KW.   +4 more
europepmc   +1 more source

Regional nonsense constraint offers biological and clinical insights into genetic disease. [PDF]

Nat Commun
Blakes AJM, Whiffin N, Johnson CA, Ellingford JM, Banka S.   +4 more
europepmc   +1 more source

Integrative and accurate annotations enhance current nonsense-mediated mRNA decay rules. [PDF]

Nucleic Acids Res
Iha H, Kikutake C, Suyama M.
europepmc   +1 more source

A novel HBD gene mutation associated with normal-range hb A2 in β-thalassemia carriers. [PDF]

Ann Hematol
Zhang L, Yang J, Li X, Liu Y, Liu C, Duan S, Zhang L, Liu W, Chang M.   +8 more
europepmc   +1 more source

The dynamic interactions between virus infections and nonsense-mediated decay. [PDF]

Hum Mol Genet
van der Klugt T, van Gent M.
europepmc   +1 more source

Case series: a rare dominant form of β-thalassemia successfully treated by luspatercept. [PDF]

Ann Hematol
Allard PN, Kulozik AE, Kunz JB.
europepmc   +1 more source