Results 131 to 140 of about 2,306,587 (203)

Targeting <i>EZH2</i> oncogenic splicing: decoding the regulatory network and antisense correction. [PDF]

Genes Dev
Islam MR, Nagar P, McNaughton N, Heeamoni SA, Hasan MM, Kandel S, Mukta IJ, Tsakiroglou P, Dalton WB, Abdel-Wahab O, Krainer AR, Rahman MA.   +11 more
europepmc   +1 more source

Identification of inhibitors of nonsense-mediated mRNA decay (NMD) and use as a therapeutic approach for some genetic diseases

, 2011
Le NMD (nonsense-mediated mRNA decay) est un mécanisme qui reconnaît et dégrade les ARNm portant un codon stop prématuré afin d’empêcher la synthèse de protéines tronquées qui pourraient avoir des effets néfastes pour la cellule ou tout simplement être non fonctionnelles.
openaire   +1 more source

Signatures of nonsense-mediated mRNA decay but no evidence for transcriptional adaptation associated with protein-truncating variants in wild yeast diploids. [PDF]

Mol Biol Evol
Marszałek M, Babik W, Korona R, Tomala K.   +3 more
europepmc   +1 more source

Beyond Coding Variants: RNA-Level Mechanisms in Human Disease and Precision Therapeutics. [PDF]

Genes (Basel)
Goel H.
europepmc   +1 more source

<i>ADNP</i>-Related Neurodevelopmental Disorder: The First Turkish Case Series with Novel Variants and Reduced Intrafamilial Penetrance. [PDF]

Diagnostics (Basel)
Kablan A, Sezer A, Deniz A, Taşdelen E, Dinçsoy Bir F, Kolkıran A, Ataseven Kulalı M, Teralı K, Işık E.   +8 more
europepmc   +1 more source

Pediatric Familial Cerebral Cavernous Malformation Associated With a Novel KRIT1 Initiation-Region Frameshift Variant. [PDF]

Mol Genet Genomic Med
Yayıcı Köken Ö, Yanartaş MS, Aygün H, Ceylan AC, Karaali K, Kazan MS.   +5 more
europepmc   +1 more source

An antisense antidote to oncogenic poison exons. [PDF]

Genes Dev
Arvola RM, Singh G.
europepmc   +1 more source

Nonsense mutations can increase mRNA levels. [PDF]

Biol Open
Owuamalam PO, Hossain MN, Brogna S.
europepmc   +1 more source

Beyond quality control: biological roles of nonsense-mediated RNA decay. [PDF]

EMBO J
Tan K, Wilkinson MF.
europepmc   +1 more source

The function of mRNA quality control in aging and age-related diseases. [PDF]

J Biol Chem
Ha SG, Kwon HC, Lee J, Kim HJ, Lee SV.
europepmc   +1 more source