Results 21 to 30 of about 1,587,098 (210)
Identification of novel neutralizing determinants for protection against HCV
Hepatology, EarlyView., 2022 Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua +12 more
wiley +1 more source
Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]
, 2013 Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Estes, M. K. +4 more
core +3 more sources
Flavivirus Capsid Proteins Inhibit the Interferon Response
Viruses, 2022 Zika virus (ZIKV) establishes persistent infections in multiple human tissues, a phenomenon that likely plays a role in its ability to cause congenital birth defects and neurological disease. Multiple nonstructural proteins encoded by ZIKV, in particular
Adriana M. Airo +9 more
doaj +1 more source
Dramatic Improvement in the Efficacy of Foot and Mouth Disease vaccines by Co-administration of Echinacea [PDF]
Veterinary Medical Journal - Giza, 2011 Background. Foot and mouth disease (FMD) is a highly contagious and economically devastating disease of cloven-hoofed animals. The goal of the present study was to increase the efficacy of FMD vaccines by co-administration of Echinacea (herbal medicine ...
Ismael B, ELNabtity M, Aly A
doaj +1 more source
Viruses, 2022 Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in humans globally. Considered for a long while a public health issue only in developing countries, the HEV infection is now a global public health concern.
Adeline Goulet +3 more
doaj +1 more source
Mobility and Interactions of Coronavirus Nonstructural Protein 4 [PDF]
Journal of Virology, 2011 ABSTRACT Green fluorescent protein (GFP)-tagged mouse hepatitis coronavirus nonstructural protein 4 (nsp4) was shown to localize to the endoplasmic reticulum (ER) and to be recruited to the coronavirus replicative structures. Fluorescence loss in photobleaching and fluorescence recovery after photobleaching experiments demonstrated that while
Hagemeijer, Marne C +5 more
openaire +3 more sources
Arm race between Rift Valley fever virus and host
Frontiers in Immunology, 2022 Rift Valley fever (RVF) is a zoonotic disease caused by Rift Valley fever virus (RVFV), an emerging arbovirus within the Phenuiviridae family of Bunyavirales that has potential to cause severe diseases in both humans and livestock.
Xiao Wang +8 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2021 The highly infectious disease COVID-19 caused by the Betacoronavirus SARS-CoV-2 poses a severe threat to humanity and demands the redirection of scientific efforts and criteria to organized research projects.
Nadide Altincekic +178 more
doaj +1 more source
The Coronavirus Nonstructural Proteins [PDF]
, 1995 The definition of a group of virus-coded proteins/polypeptides, the nonstructural, as those not found in virions is crude, but has some merit in that it immediately focuses attention on the potential difficulties encountered in defining them. It leaves aside the practical difficulties implicit in attempting to detect small amounts of virus-coded ...
T. D. K. Brown, I. Brierley
openaire +1 more source
Emerging Microbes and Infections, 2022 Zika virus (ZIKV) has been circulating in human networks over 70 years since its first appearance in Africa, yet little is known about whether the viral 3′-terminal sequence and nonstructural (NS) protein diverged genetically from ancient ZIKV have ...
Hae-Gwang Jung +11 more
doaj +1 more source