Results 41 to 50 of about 3,775 (250)

Outsmarted by nooptropics? An investigation into the thermal degradation of modafinil, modafinic acid, adrafinil, CRL-40,940 and CRL-40,941 in the GC injector: formation of 1,1,2,2-tetraphenylethane and its tetra fluoro analog. [PDF]

2-[(Diphenylmethyl)sulfinyl]acetamide (modafinil) is commonly prescribed for the treatment of narcolepsy and increasing popularity and off-label use as a cognitive enhancer resulted in a reputation as an intelligence boosting ‘wonder drug’.
Battledaya, Becue, Biovin, Bohne, Bohnenberger, Bowie, Burnat, Cao, Dackis, Dackis, Dackis, Dietz, Dolomanov, Dougherty, Duan, Dubey, Forrester, Hart, Jean-Pierre, Jockusch, Johnstone, Jurie, Kahbazi, Kampman, Kelley, Khuddus, Kumar, Lange, Ma, Maher, Malcolm, McKinney, Milgram, Minkwitz, Minzenberg, Moreau, Ondo, Rabkin, Randall, Robertson, Schmitz, Schmitz, Sheldrick, Topolyan, Tseng, Tsujikawa, Tsurugi, Turner, Williams, Williams, Wu   +50 more
core   +1 more source

Interaction of vitamin D, homocystein and dental diseases

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
The 1,2,4-triazole nucleus is resistant to metabolism and is an important pharmacophore; it can increase solubility and improve the pharmacokinetic and pharmacodynamic profile of drugs.
Ye. O. Karpun , Yu. V. Karpenko, M. V. Parchenko, O. A. Bihdan   +3 more
doaj   +1 more source

Voltage- and Temperature-Dependent Allosteric Modulation of α7 Nicotinic Receptors by PNU120596 [PDF]

, 2017
This is the final version of the article. Available from Frontiers Media via the DOI in this record.Alpha7 nicotinic acetylcholine receptors (α7 nAChR) are widely distributed throughout the central nervous system and are found at particularly high levels
Brown, JT, Dunlop, J, Randall, AD, Sitzia, F   +3 more
core   +1 more source

Surveillance of Phenibut in Wastewater During a Brazilian Carnival

Drug Testing and Analysis, Volume 18, Issue 2, Page 192-197, February 2026.
This study reports the first detection of phenibut in Brazilian wastewater. Phenibut, a substance readily sold online to improve concentration, reaches wastewater treatment plants (WWTPs) after consumption by the population. Samples from WWTPs in the cities of Recife and Olinda in Northeastern Brazil were collected during the world's largest Carnival ...
Bruna R. de S. Gomes, Ana Flávia B. de Oliveira, Aline de Melo Vieira, Dhayaalini Nadarajan, Richard Bade, Jandyson M. Santos   +5 more
wiley   +1 more source

Pharmacological Properties, Molecular Mechanisms, and Pharmaceutical Development of Asiatic Acid: A Pentacyclic Triterpenoid of Therapeutic Promise

Frontiers in Pharmacology, 2018
Asiatic acid (AA) is a naturally occurring aglycone of ursane type pentacyclic triterpenoids. It is abundantly present in many edible and medicinal plants including Centella asiatica that is a reputed herb in many traditional medicine formulations for ...
Mohamed Fizur Nagoor Meeran, Sameer N. Goyal, Kapil Suchal, Charu Sharma, Chandragouda R. Patil, Shreesh K. Ojha   +5 more
doaj   +1 more source

Health Effects of Bee Products: A Comprehensive Review

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Nutritional composition of bee products and some health effects. ABSTRACT Honey, bee pollen, propolis, bee bread, royal jelly, bee venom, beeswax, and apilarnil are among the bee‐derived products that may serve health‐related purposes, as they exhibit various biological activities such as antibacterial, antiviral, antifungal, antioxidant, anti ...
Nevin Sanlier, Elif Yildiz Kaya, Ikbal Irem Yucel   +2 more
wiley   +1 more source

Effect of short time captopril administration on spatial memory in aging rats [PDF]

, 2015
Introduction: The brain renin-angiotensin system (RAS) has been reported having a pathological role in age-related impairment in learning and memory. Therefore, angiotensin converting enzyme inhibitors (ACEi) are expected to have positive ef fects on ...
Bakhshandeh, F., Ganji, F., Sepehri, H.
core  

Molecular Insights Into Repurposed Drug Interactions With HDAC11 for Advancing Epigenetic Therapeutics in Cancer and Neurodegenerative Diseases

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Histone deacetylase 11 (HDAC11) is a member of the HDAC family that plays a crucial role in epigenetic regulation, influencing key cellular processes like transcription, differentiation, and proliferation. Abnormal expressions and functions of HDAC11 have been described in various diseases, including neurodegenerative diseases and cancer, highlighting ...
Yinsheng Yang, Khalida Ahmed Mohammed Ahmed, Khuzin Dinislam, Pratibha Prasad, Akhtar Atiya, Sohini Basu Roy   +5 more
wiley   +1 more source

Nootropic and Adaptogenic Effect of Combined Use of Cortexin with Polyunsaturated Fatty Acids Concentrate under Experimental Dislipidemia

Acta Biomedica Scientifica, 2019
Background. We studied the effect of combined application of omega-3 polyunsaturated fatty acid concentrate, based on seals fat, with parenteral administration of brain cortex polypeptide preparation on cognitive-research reactions and adaptation of rats
Tatyana I. Sangadieva, Galina P. Lamazhapova, Erzhena V. Syngeeva   +2 more
doaj   +1 more source

The Yekaterinburg headache initiative: an interventional project, within the Global Campaign against Headache, to reduce the burden of headache in Russia. [PDF]

, 2013
BACKGROUND: As major causes of global public ill-health and disability, headache disorders are paradoxically ignored in health policy and in planning, resourcing and implementing health services. This is true worldwide.
Lebedeva, ER, Olesen, J, Osipova, VV, Steiner, TJ, Tabeeva, GR, Volkova, LI   +5 more
core   +1 more source