Results 51 to 60 of about 3,775 (250)

Advances in Pharmacological Insights of Borago officinalis: A Comprehensive Review

open access: yesBiological Diversity, Volume 2, Issue 4, Page 193-205, December 2025.
ABSTRACT Recent growth in phytotherapy and product‐based drug development has increased interest in this plant because of its broad pharmacological activity. This review aims to examine the pharmacological activities, mechanisms, and potential applications of Borago officinalis, focusing on its primary bioactive constituents and therapeutic ...
Zahra Sufwan   +2 more
wiley   +1 more source

The modern view of the idea of gamma-aminobutyric acid and its metabolite use to restore the motor function

open access: yesPatologìâ, 2015
Aim. The literature review is devoted to the idea of using gamma-aminobutyric acid and its metabolites as medicines in conditions of peripheral nervous system injury.
А. G. Rodinskij   +3 more
doaj   +1 more source

Choline and Choline alphoscerate Do Not Modulate Inflammatory Processes in the Rat Brain [PDF]

open access: yes, 2017
Choline is involved in relevant neurochemical processes. In particular, it is the precursor and metabolite of acetylcholine (ACh). Choline is an essential component of different membrane phospholipids that are involved in intraneuronal signal ...
Amenta, Francesco   +4 more
core   +2 more sources

Structure‐Guided Identification and Evaluation of Epalrestat and Ranirestat‐Like Compounds Against Aldose Reductase: Therapeutic Management of Diabetic Neuropathy

open access: yesChemistryOpen, Volume 14, Issue 12, December 2025.
Structure‐based virtual screening of PubChem compounds identifies two novel epalrestat and ranirestat‐like inhibitors with improved affinity and pharmacokinetic profiles targeting aldose reductase. Molecular docking, ADMET filtering, and 500‐ns molecular dynamics simulations confirm the stability and interaction specificity of the candidates ...
Mohd Shahnawaz Khan   +3 more
wiley   +1 more source

Neuroprotective Effect of Ashtanga Ghrita on Spatial Learning and Memory in Scopolamine-Induced Amnesia in Rat Model

open access: yesJournal of Ayurveda
Introduction: Ashtanga Ghrita (AG), Medhya Rasayana (nervine rejuvenator), is used for the treatment of neurodegenerative disorders. The contents of AG specifically act on Medha (intellect), whereas the lipid part, Go Ghrita, serves as a medium for the ...
Yashika Singh, DevNath Singh Gautam
doaj   +1 more source

Performance Enhancement at the Cost of Potential Brain Plasticity: Neural Ramifications of Nootropic Drugs in the Healthy Developing Brain

open access: yesFrontiers in Systems Neuroscience, 2014
Cognitive enhancement is perhaps one of the most intriguing and controversial topics in neuroscience today. Currently, the main classes of drugs used as potential cognitive enhancers include psychostimulants (methylphenidate, amphetamine), but ...
Kimberly R. Urban, Wen-Jun eGao
doaj   +1 more source

Фармакотерапевтичний ефект стреспротекторів у віковому аспекті [PDF]

open access: yes, 2017
The data of the literature and the results of original experimental observations concerning the age aspects of stress reactions that accompany a person from birth to adulthood are given. Stress in children is emotional and is characterized by an increase
Hladkykh, Fedir   +3 more
core   +3 more sources

Pharmaceutical Neuroenhancement in the Quest for Worth at Work

open access: yesSociological Inquiry, Volume 95, Issue 4, Page 834-850, November 2025.
This article examines the use of psychoactive substances for cognitive enhancement in the context of work. By drawing upon existing qualitative research and sociological theories on meaningful work, valuation, and human agency, I explore cultural and institutional processes encouraging individuals to engage in such practices and argue that ...
Sigita Doblytė
wiley   +1 more source

Diagnosis and treatment of benign paroxysmal positional vertigo in common clinical practice

open access: yesТерапевтический архив, 2017
Aim. To analyze typical medical practice in managing patients with benign paroxysmal positional vertigo (BPPV). Subjects and methods. 33 patients (5 men and 28 women; mean age, 58 years) with BPPV who had been referred for consultation to the Medical ...
N V Lebedeva   +3 more
doaj   +1 more source

Synergy of piracetam and aminalon in the cerebroprotective effect of olatropyl.

open access: yesMedičnì Perspektivi, 2018
Optimization of pharmacotherapy of neurological and psychosomatic diseases led to the creation of com­bined medicines containing two or more components with different mechanisms of action, differently affecting the pathogenesis and clinical ...
V. I. Mamchur, S. N. Dronov
doaj   +1 more source

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