Results 1 to 10 of about 424,128 (151)

Molecular features of prenylated (iso)flavonoids from Fabaceae in relation to their potential NorA inhibition in Staphylococcus aureus [PDF]

open access: yesFrontiers in Pharmacology
BackgroundThe overexpression of the NorA efflux pump is known to be an important factor in the antimicrobial resistance mechanism of Staphylococcus aureus. Therefore, NorA inhibition can help disarm this pathogen and tackle antimicrobial resistance.
Marina Ika Irianti   +5 more
doaj   +2 more sources

Genetic Diversity of norA, Coding for a Main Efflux Pump of Staphylococcus aureus

open access: yesFrontiers in Genetics, 2019
NorA is the best studied efflux system of Staphylococcus aureus and therefore frequently used as a model for investigating efflux-mediated resistance in this pathogen.
Sofia Santos Costa   +2 more
exaly   +3 more sources

Computational Insights and In Vitro Validation of Antibacterial Potential of Shikimate Pathway-Derived Phenolic Acids as NorA Efflux Pump Inhibitors

open access: yesMolecules, 2022
The expression of the efflux pump systems is the most important mechanism of antibiotic resistance in bacteria, as it contributes to reduced concentration and the subsequent inactivity of administered antibiotics.
Njabulo J Gumede, Saheed Sabiu
exaly   +3 more sources

From home to homelessness: A reflection on Nora’s possible post-departure feminist life in A Doll’s House by Henrik Ibsen

open access: yesEdulite: Journal of English Education, Literature, and Culture, 2022
In Henrik Ibsen’s A Doll’s House, Nora’s departure from home being hurt by her husband’s behavior appears to be the most important event of the drama igniting so far a wide critical parlances of Feminist array that appreciate the departure as Nora’s ...
Md. Abu Saleh Nizam Uddin
doaj   +1 more source

C-2 phenyl replacements to obtain potent quinoline-based Staphylococcus aureus NorA inhibitors

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2020
NorA is the most studied efflux pump of Staphylococcus aureus and is responsible for high level resistance towards fluoroquinolone drugs. Although along the years many NorA efflux pump inhibitors (EPIs) have been reported, poor information is available ...
Tommaso Felicetti   +12 more
doaj   +1 more source

NORAS UTVIKLING MOT «JÆVN NATURSANDHED»: Utviklingen av realistisk skuespillerkunst sett gjennom Henrik Ibsens Nora

open access: yesTeatervitenskapelige Studier, 2022
Henrik Ibsen’s dramaturgy, physical score and knowledge of theatre changed the way actors work to portray a character. This historiographic article addresses the development of acting methods seen through Henrik Ibsen’s Nora and Ibsen’s revolutionary ...
Agnete G. Haaland
doaj   +1 more source

Le sette città di Nora. Lo scavo dell’Università di Milano in una realtà urbana pluristratificata

open access: yesLanx, 2013
Un’introduzione al convegno. Sono tipici di Nora i molti strati, che testimoniano della lunga vita della città. Nell’area centrale, gli scavi dell’Università di Milano hanno mostrato almeno sette fasi urbane sovrapposte, ciascuna con propri aspetti ...
Giorgio Bejor
doaj   +1 more source

Abgrenzung deutscher Arbeitsmarktregionen

open access: yesRaumforschung und Raumordnung, 2006
Functional delineated labour market regions are needed for regional economic analyses. In dependence of the definition of regions economic regions in space can be seen as “rich” or “poor” areas.
Hans-Friedrich Eckey   +2 more
doaj   +1 more source

Nora Virus VP4b and ORF1 Circulate in Hemolymph of Infected D. melanogaster with Coordinate Expression of Vago and Vir-1

open access: yesVaccines, 2020
Study of the novel RNA virus, Nora virus, which is a persistent, picorna-like virus that replicates in the gut of Drosophila melanogaster offers insight into human innate immunity and other picorna-like viruses.
Amanda Macke   +3 more
doaj   +1 more source

Remodeling of t-system and proteins underlying excitation-contraction coupling in aging versus failing human heart

open access: yesnpj Aging and Mechanisms of Disease, 2021
It is well established that the aging heart progressively remodels towards a senescent phenotype, but alterations of cellular microstructure and their differences to chronic heart failure (HF) associated remodeling remain ill-defined.
Yankun Lyu   +13 more
doaj   +1 more source

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