Results 21 to 30 of about 5,409,842 (383)

Inhibition of the norA gene expression and the NorA efflux pump by the tannic acid

Scientific Reports, 2023
The NorA efflux pump of Staphylococcus aureus is known to play a major role in the development of resistance against quinolone drugs by reducing their concentration inside target pathogens.
S. Tintino, P. Wilairatana, Veruska Cíntia Alexandrino de Souza, Julia Mariana Assis da Silva, P. S. Pereira, Cícera Datiane de Morais Oliveira-Tintino, Y. D. de Matos, João Tavares Calixto Júnior, V. de Queiroz Balbino, J. P. Siqueira-Júnior, I. Menezes, A. Siyadatpanah, H. D. M. Coutinho, T. C. L. Balbino   +13 more
semanticscholar   +1 more source

Efflux pump inhibitor combined with ofloxacin decreases MRSA biofilm formation by regulating the gene expression of NorA and quorum sensing

RSC Advances, 2023
Carbonyl cyanide p-nitrophenylhydrazone (2e) displayed a lone or synergistic efficacy against MRSA (RSC Adv., 2020, 10, 17854). In this work, the synergistic mechanism of 2e with ofloxacin was studied.
Xueer Lu, G. Wang, Yunfeng Xie, Wenjian Tang, Biyong Liu, Jing Zhang   +5 more
semanticscholar   +1 more source

Inhibition of Staphylococcus pseudintermedius Efflux Pumps by Using Staphylococcus aureus NorA Efflux Pump Inhibitors

Antibiotics, 2023
One promising approach in treating antibiotic-resistant bacteria is to “break” resistances connected with antibacterial efflux by co-administering efflux pump inhibitors (EPIs) with antibiotics.
Elisa Rampacci, Tommaso Felicetti, Giada Cernicchi, V. Stefanetti, S. Sabatini, F. Passamonti   +5 more
semanticscholar   +1 more source

Occurrence and Variability of the Efflux Pump Gene norA across the Staphylococcus Genus

International Journal of Molecular Sciences, 2022
NorA is one of the main native MDR efflux pumps of Staphylococcus aureus, contributing to reduced susceptibility towards fluoroquinolones and biocides, but little is known about its variability within S.
C. Ferreira, P. Abrantes, S. S. Costa, M. Viveiros, I. Couto   +4 more
semanticscholar   +1 more source

Bizarre Parosteal Osteochondromatous Proliferation (Nora Lesion): A Narrative Review

Acta medica Lituanica, 2022
. Background: Bizarre parosteal osteochondromatous proliferation (BPOP), or Nora lesion, is a rare proliferative disease arising from the parosteal region of bones.
Ipponi Edoardo, Ferrari Elisa, Ruinato Alfio Damiano, Devi Silvia, C. Rodolfo, Andreani Lorenzo   +5 more
semanticscholar   +1 more source

Modulation of Drug Resistance by Furanochromones in NorA Overexpressing Staphylococcus Aureus

Evidence-Based Complementary and Alternative Medicine, 2022
Khellin and visnagin are natural furanochromones that photoreact with DNA. Khellin has been used in the treatment of vitiligo and psoriasis, as well as in the treatment of angina pectoris and asthma due to its potent action as a coronary vasodilator and ...
D. F. Rodrigues, Nathalie H P B Borges, Carlos Emídio S Nogueira, J. Tavares, D. Arcanjo, H. M. Barreto, J. P. Siqueira-Júnior   +6 more
semanticscholar   +1 more source

A Case of Severe Falciparum Malaria in a Returned Traveler [PDF]

Malaysian Family Physician, 2020
Primary care providers should be alert to travel-related infections. Around 10-40% of returning travelers from all destinations and 15-70% of travelers from tropical settings experience ill health, either overseas or upon returning home.1 A systematic ...
Qin Jian Low, Wai Kar Lau, Tzyy Huei Lim, Ri An Lee, Seng Wee Cheo   +4 more
doaj  

Chalcone Derivatives as Potential Inhibitors of P-Glycoprotein and NorA: An In Silico and In Vitro Study

BioMed Research International, 2022
The human P-glycoprotein (P-gp) and the NorA transporter are the major culprits of multidrug resistance observed in various bacterial strains and cancer cell lines, by extruding drug molecules out of the targeted cells, leading to treatment failures in ...
M. Le, D. Trinh, Trieu-Du Ngo, V. Tran-Nguyen, Dac-Nhan Nguyen, Tung Hoang, Hoang-Minh Nguyen, Tran-Giang-Son Do, Tan Thanh Mai, T. Tran, K. Thai   +10 more
semanticscholar   +1 more source

Spatial adaptation in heteroscedastic regression: Propagation approach [PDF]

, 2011
The paper concerns the problem of pointwise adaptive estimation in regression when the noise is heteroscedastic and incorrectly known. The use of the local approximation method, which includes the local polynomial smoothing as a particular case, leads to
Serdyukova, Nora
core   +1 more source

New Perspectives on the Sanctuary of Aesculapius in Nora (Sardinia): From Photogrammetry to Visualizing and Querying Tools

Open Archaeology, 2019
The ritual space of the Sanctuary of Aesculapius in Nora (Sardinia) is the main focus of a recent archaeological campaign led by the Cultural Heritage Department of the University of Padova.
Carraro Filippo, Marinello Alessandra, Morabito Daniele, Bonetto Jacopo   +3 more
doaj   +1 more source