Frontiers in Neuroscience, 2021 Noradrenaline is an important neuromodulator in the cerebellum. We previously found that noradrenaline depressed cerebellar Purkinje cell activity and climbing fiber–Purkinje cell synaptic transmission in vivo in mice.
Bing-Xue Li +11 more
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In Vitro Neurochemical Assessment of Methylphenidate and Its “Legal High” Analogs 3,4-CTMP and Ethylphenidate in Rat Nucleus Accumbens and Bed Nucleus of the Stria Terminalis [PDF]
Frontiers in Psychiatry, 2018 3,4-dichloromethylphenidate (3,4-CTMP) and ethylphenidate are new psychoactive substances and analogs of the attention deficit medication methylphenidate. Both drugs have been reported on online user fora to induce effects similar to cocaine.
Colin Davidson +4 more
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Chronic voluntary exercise induces plasticity of noradrenaline-activated dopamine D1-like receptor signaling [PDF]
Molecular BrainPhysical exercise has lasting positive influence on mental health. However, its cellular substrate remains to be elucidated. Recently, dopamine D1-like receptor activation induced by noradrenaline has been suggested to underlie exercise-dependent ...
Katsunori Kobayashi
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The influence of thirty-degree leg elevation on noradrenaline requirements administered as a prophylactic variable infusion during cesarean delivery, an open-label randomized controlled trial [PDF]
Journal of Anesthesia, Analgesia and Critical CareBackground Spinal anesthesia is the preferred technique for elective cesarean delivery; however, it is frequently associated with spinal anesthesia-induced hypotension.
Mina Adolf Helmy +3 more
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The influence of μ-opioid and noradrenaline reuptake inhibition in the modulation of pain responsive neurones in the central amygdala by tapentadol in rats with neuropathy [PDF]
, 2015 Treatments for neuropathic pain are either not fully effective or have problematic side effects. Combinations of drugs are often used. Tapentadol is a newer molecule that produces analgesia in various pain models through two inhibitory mechanisms, namely
Dickenson, AH, Friend, LV, Gonçalves, L
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Adrenergic signals influence proteomic responses in breast cancer cells [PDF]
Frontiers in NeuroscienceIntroductionBreast cancer remains a major health challenge due to its molecular heterogeneity and complex interactions with the tumor microenvironment.
Manuel Carrasco +4 more
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Cells, 2023 In the cerebral cortex, glutamate activates NMDA receptors (NMDARs), localized in noradrenergic neurons, inducing noradrenaline release that may have a permissive effect on glutamatergic transmission, and therefore, on the modulation of long-term ...
Clara Quintas +2 more
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EJNMMI Research, 2023 Background The neuropathological changes of early Alzheimer’s disease (AD) include neurodegenerative loss of noradrenaline neurons in the locus coeruleus with decreasing noradrenaline availability in their projection areas such as the hippocampus.
Takayuki Sakai +10 more
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Frontiers in Cellular Neuroscience, 2021 Noradrenaline is a major neuromodulator in the central nervous system (CNS). It is released from varicosities on neuronal efferents, which originate principally from the main noradrenergic nuclei of the brain – the locus coeruleus – and spread throughout
Jérôme Wahis +5 more
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