Results 101 to 110 of about 147,087 (295)

Adrenergic signals influence proteomic responses in breast cancer cells

open access: yesFrontiers in Neuroscience
IntroductionBreast cancer remains a major health challenge due to its molecular heterogeneity and complex interactions with the tumor microenvironment.
Manuel Carrasco   +4 more
doaj   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili   +6 more
wiley   +1 more source

The effect of α-methyldopa on excretion of noradrenaline metabolites [PDF]

open access: yes, 1967
The effect of α-methyldopa on the rate of release of noradrenaline metabolites in patients with essential hypertension has been examined. The excretion of normetadrenaline increases during the first few hr after a dose of α-methyldopa while α ...
R ROBINSON, A W STOTT
core   +1 more source

Optogenetic stimulation of the locus coeruleus enhances appetitive extinction in rats

open access: yeseLife
Extinction is a specific example of learning where a previously reinforced stimulus or response is no longer reinforced, and the previously learned behaviour is no longer necessary and must be modified.
Simon Lui   +2 more
doaj   +1 more source

Environmental impact of antidepressants: Is a new prescription framework possible?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Antidepressants such as venlafaxine and sertraline pose high risks to water ecosystems. As depressive disorders and other mental health conditions become increasingly prevalent worldwide, prescription and environmental presence of these pharmaceuticals continue to rise. This study explores the practical viability of a new framework for prescribing
Matilde Bianconi   +5 more
wiley   +1 more source

Dopamine versus Noradrenaline in Septic Shock [PDF]

open access: yes, 2011
BackgroundThe ‘Surviving Sepsis’ Campaign guidelines recommend the use of dopamine or noradrenaline as the first vasopressor in septic shock. However, information that guides clinicians in choosing between dopamine and noradrenaline as the first ...
Bo Xu; Peter MacCallum Cancer Institute   +1 more
core   +1 more source

Inhibition of pilocarpine-induced salivation in rats by central noradrenaline [PDF]

open access: yes, 2002
Peripheral treatment with cholinergic or adrenergic agonists results in salivation and the possibility of synergy between cholinergic and adrenergic efferent mechanisms in the control of salivation has been proposed. Central injections of the cholinergic
Moreira, T. D.   +6 more
core   +1 more source

THE ACTION OF NORADRENALINE [PDF]

open access: yesBritish Journal of Pharmacology and Chemotherapy, 1949
J H, BURN, D E, HUTCHEON
openaire   +2 more sources

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

open access: yesBMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma   +8 more
wiley   +1 more source

3-Hydroxybutyrate coinfused with noradrenaline decreases resulting plasma levels of noradrenaline in Wistar rats [PDF]

open access: yes
Pentobarbital-anaesthetized male Wistar rats were infused with 6microgkg-1min-1 of noradrenaline. The infusion was supplemented with 8.5 mgkg-1min-1 of D-3-hydroxybutyrate (3-OHB) for 15 min in order to determine its effect on the adrenergic response of ...
Fernández López, José Antonio   +7 more
core  

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