Results 131 to 140 of about 41,607 (263)
Stress Suppression of Growth Hormone Secretion in the Rat: Effects of Disruption of Inhibitory Noradrenergic Afferents to the Median Eminence [PDF]
Trevor A. Day +2 more
openalex +1 more source
Metformin Restores Mitochondrial Function and Neurogenesis in POLG Patient‐Derived Brain Organoids
Patient‐derived POLG‐mutant cortical organoids reveal neuronal subtype‐specific mitochondrial and synaptic defects, with dopaminergic neurons most affected. Metformin treatment restores neuronal identity, mitochondrial function, and excitability, increased mtDNA maintenance, and reprogrammed metabolism via TCA and redox pathways.
Zhuoyuan Zhang +6 more
wiley +1 more source
Induction of noradrenergic supersensitivity following cordotomy in neonatal rat spinal motoneurons.
Hitoshi Kadotani
openalex +2 more sources
Activation of spinal dorsal horn astrocytes by noxious stimuli involves descending noradrenergic signaling [PDF]
Riku Kawanabe +3 more
openalex +1 more source
Dexmedetomidine at 25 µg/kg effectively reverses working and spatial memory deficits in a streptozotocin (STZ)‐induced rat model of Alzheimer's disease, restoring Y‐maze alternation and Morris Water Maze performance. Higher doses show no clear benefit, highlighting Dex‐25 as a promising neuroprotective candidate.
Mina Mohasel‐Roodi +5 more
wiley +1 more source
This study demonstrates the protective effect of acute restraint stress (ARS) against hepatic ischemia–reperfusion injury (HIRI) in mice and investigates its specific neuroendocrine mechanisms. During ARS, excitability of PVNCRH neurons significantly increases, which drives HPA axis to release corticosterone, thereby reducing hepatic inflammation and ...
Xiaoqi Lin +12 more
wiley +1 more source
Bidirectional Pathogenesis Between AD and Periodontitis. Periodontal pathogens reach the brain via hematogenous/trigeminal/oral–intestinal pathways, triggering neuroinflammation and Aβ plaques to drive AD. Conversely, AD disrupts bone homeostasis (via Aβ, endocrine/autonomic dysregulation) to aggravate periodontitis.
Weidong Zhang +5 more
wiley +1 more source
Synergetic effect of a DSP4-induced locus coeruleus lesion and systemic LPS exacerbates substantia nigra dopaminergic neuron loss. [PDF]
Şimşek F +7 more
europepmc +1 more source
Noradrenergic transmission (reply) [PDF]
G. D. S. HIRST, T. O. NEILD
openaire +1 more source

