Results 171 to 180 of about 7,845 (216)
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Noradrenergic and adrenergic functioning in autism
Biological Psychiatry, 1994A neurochemical assessment of noradrenergic and adrenergic functioning was carried out with autistic patients and normal control individuals. Norepinephrine and related compounds were measured in autistic (n = 17 unmedicated, 23 medicated; age range 9-29 years old) and normal controls (n = 27; age range 9-36 years old).
Donald J. Cohen +4 more
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Noradrenergic and serotoninergic depression?
Journal of Affective Disorders, 1993The aim of this study was to test the hypothesis of noradrenergic and serotoninergic depressive subtypes. For this purpose, the correlation between three variables was investigated: urinary 3-methoxy-4-hydroxyphenylglycol (MHPG), dexamethasone suppression test (DST), and clinical response profiles to clomipramine and maprotiline, the effects of which ...
Alp Üçok +8 more
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AMPHETAMINE AND NORADRENERGIC REWARD PATHWAYS
Biochemical Pharmacology, 1973Publisher Summary This chapter reviews amphetamine and noradrenergic reward pathways. The effects of norepinephrine, and dopamine on self-stimulation were directly examined by injecting these agents in the lateral ventricle through permanently-indwelling cannulas.
C. David Wise, Larry Stein
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Progress in Neurobiology, 2006
Norepinephrine is involved in intrinsic control of pain. Main sources of norepinephrine are sympathetic nerves peripherally and noradrenergic brainstem nuclei A1-A7 centrally. Peripheral norepinephrine has little influence on pain in healthy tissues, whereas in injured tissues it has variable effects, including aggravation of pain.
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Norepinephrine is involved in intrinsic control of pain. Main sources of norepinephrine are sympathetic nerves peripherally and noradrenergic brainstem nuclei A1-A7 centrally. Peripheral norepinephrine has little influence on pain in healthy tissues, whereas in injured tissues it has variable effects, including aggravation of pain.
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Genetic Manipulation of Noradrenergic Neurons
The Journal of Pharmacology and Experimental Therapeutics, 2002The neurotransmitter norepinephrine has been the focus of intense investigation for nearly a century. With advances in technology come novel approaches for testing hypotheses about the physiological roles of norepinephrine and the genes involved in norepinephrine (NE) biosynthesis, metabolism, and noradrenergic signaling.
David Robertson, Robert P. Carson
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Noradrenergic mechanisms in the prefrontal cortex
Journal of Psychopharmacology, 1997There is growing evidence that noradrenergic inputs to the prefrontal cortex (PFC) play an important role in regulating its function. This paper reviews the pharmacological control of noradrenaline (NA) release in this region, with particular reference to our studies using brain microdialysis, and also describes how NA levels are modulated by ...
M. D. Lalies +3 more
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Noradrenergic Challenges in the Affective Disorders
Journal of Clinical Psychopharmacology, 1981The rationale for the use of noradrenergic challenges, i.e., administration of psychopharmacological agents that alter noradrenergic activity, is reviewed in relation to evidence implicating the noradrenergic system as important in the etiology of treatment of the affective disorders.
Thomas W. Uhde +2 more
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Noradrenergic fiber sprouting in the cerebellum
Brain Research Bulletin, 1982Abstract In order to attain a better understanding of the sprouting response of noradrenergic fibers in the central nervous system (CNS), noradrenergic innervation to the cerebellum was observed by the glyoxylic acid method after a variety of manipulations and in a genetic variant of mouse classified as “Purkinje cell degeneration” (pcd/pcd).
Kostrzewa, Richard M. +3 more
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Possible Noradrenergic Dysfunction in Schizophrenia
Brain Research Bulletin, 1994In spite of extensive studies over the last 2 decades to find direct evidence in support of the dopamine hypothesis of schizophrenia, no undisputed experimental data has been obtained. In contrast, estimation of noradrenalin (another major catecholamine) and its metabolites in postmortem brain and in the cerebrospinal fluid appears to be producing ...
Tadao Hoshino +4 more
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Noradrenergic Neurotransmission
2004Publisher Summary Sympathoneural norepinephrine (NE) satisfies the main criteria defining a neurotransmitter: a chemical released from nerve terminals by electrical action potentials that interacts with specific receptors on nearby structures to produce specific physiologic responses. Different stressors can elicit different patterns of sympathoneural
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