Results 161 to 170 of about 74,045 (223)

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

The Brain‐Gut Axis in Parkinson's Disease Pathology

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Exposure to environmental toxins induces gut dysbiosis, increases intestinal epithelial barrier permeability, immune activation, and oxidative stress, promoting α‐syn misfolding and propagation. Brainstem DMV neurons exhibit α‐syn pathology, dysregulating neuronal excitability and vagal control of GI functions.
Kudret Selin Ozkaya   +1 more
wiley   +1 more source

Effects of L‐Tyrosine Ingestion on Endurance Performance in Mentally Fatigued Cyclists

open access: yesEuropean Journal of Sport Science, Volume 26, Issue 4, April 2026.
ABSTRACT This study investigated whether L‐tyrosine supplementation enhances endurance performance in mentally fatigued cyclists. Twelve recreational cyclists completed two constant‐workload tests to exhaustion cycling tests under two experimental conditions at 80% of maximal endurance power output: L‐tyrosine ingestion (300 mg/kg) under mental fatigue
Luiz José Frota Solon‐Júnior   +3 more
wiley   +1 more source

Preoperative first-line amlodipine in phaeochromocytoma/paraganglioma: perioperative haemodynamic instability and its predictors. [PDF]

open access: yesEndocr Connect
L C   +13 more
europepmc   +1 more source

Correspondence between morphological similarity of the left lateral orbitofrontal cortex and neurotransmitter systems in adolescent males with autism

open access: yesGeneral Psychiatry, Volume 39, Issue 2, April 2026.
ABSTRACT Background Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by pronounced heterogeneity in brain structure, which limits the development of targeted interventions. Morphological brain networks (MBNs) enable the mapping of coordinated structural features across brain regions at the individual level.
Huashuang Zhang   +7 more
wiley   +1 more source

Locus coeruleus alterations in dementia with Lewy bodies: A systematic review. [PDF]

open access: yesAlzheimers Dement (N Y)
Bain A   +5 more
europepmc   +1 more source

Molecular Pathogenesis of Memory Impairment in Parkinson's Disease: An Exploration of Underlying Mechanisms

open access: yesHealth Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aim Parkinson's disease (PD) is primarily known for its motor symptoms but is increasingly recognized for its substantial cognitive effects, particularly on memory. This narrative review aims to clarify the complex molecular mechanisms contributing to memory impairment in PD by integrating findings from both animal and clinical ...
Mohammad Pourfridoni   +3 more
wiley   +1 more source

Neurotransmitter Systems in Alzheimer's Disease. [PDF]

open access: yesCurr Issues Mol Biol
Ramírez-Expósito MJ   +2 more
europepmc   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi   +5 more
wiley   +1 more source

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