Results 181 to 190 of about 10,132 (232)
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Noradrenergic Function in Suicide
Archives of Suicide Research, 2007Although abnormalities in serotonergic function have been the major focus of studies on suicidal behavior, several studies indicate that abnormalities of noradrenergic function may also be involved in the pathophysiology of suicide. In this paper, we have reviewed some of the noradrenergic studies in suicide, including studies of the biosynthetic ...
Ghanshyam N, Pandey, Yogesh, Dwivedi
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Sex and the noradrenergic system
2020The central noradrenergic system comprises multiple brainstem nuclei whose cells synthesize and release the catecholamine transmitter norepinephrine (NE). The largest of these nuclei is the pontine locus coeruleus (LC), which innervates the vast majority of the forebrain.
Neal, Joshi, Daniel, Chandler
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Noradrenergic modulation of lymphohematopoiesis
International Journal of Immunopharmacology, 1994Adrenergic agents can affect hematopoiesis after syngeneic bone marrow transplantation (BMT) in mice. In particular, chemical sympathectomy by 6-hydroxydopamine and/or administration of various doses of the alpha 1-adrenergic antagonist prazosin were shown to increase the concentration of blood granulocytes, platelets and bone marrow granulocyte ...
G J, Maestroni, A, Conti
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Noradrenergic Function in Schizophrenia
Archives of General Psychiatry, 1987Yohimbine, an alpha 2-adrenergic receptor antagonist that increases noradrenergic function, was administered to 16 healthy subjects and 18 drug-free schizophrenic patients with (n = 10) and without (n = 8) tardive dyskinesia (TD). Outcome measures of this double-blind, placebo-controlled study included changes in behavior, plasma 3-methoxy-4-hydroxy ...
W M, Glazer, D S, Charney, G R, Heninger
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Noradrenergic influences on catalepsy
Psychopharmacology, 1978Widespread depletion of forebrain noradrenaline, produced by the intracerebral injection of 4 microgram of 6-hydroxydopamine into the fibres of the dorsal noradrenergic bundle, potentiated the catalepsy induced by 20 mg/kg of morphine and severely attenuated the catalepsy induced by two separate cholinergic agonists, arecoline and pilocarpine.
S T, Mason, D C, Roberts, H C, Fibiger
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Progress in Neurobiology, 2006
Norepinephrine is involved in intrinsic control of pain. Main sources of norepinephrine are sympathetic nerves peripherally and noradrenergic brainstem nuclei A1-A7 centrally. Peripheral norepinephrine has little influence on pain in healthy tissues, whereas in injured tissues it has variable effects, including aggravation of pain.
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Norepinephrine is involved in intrinsic control of pain. Main sources of norepinephrine are sympathetic nerves peripherally and noradrenergic brainstem nuclei A1-A7 centrally. Peripheral norepinephrine has little influence on pain in healthy tissues, whereas in injured tissues it has variable effects, including aggravation of pain.
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The regulation of the noradrenergic neuron
Journal of Psychiatric Research, 1974Publisher Summary This chapter discusses the regulation of the noradrenergic neuron. A number of regulatory processes exist that influence the biosynthesis of catecholamines in adrenergic neurons. The large number of events, occurring in a highly synchronized fashion, implies a wide variety of possible regulatory sites.
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Noradrenergic and adrenergic functioning in autism
Biological Psychiatry, 1994A neurochemical assessment of noradrenergic and adrenergic functioning was carried out with autistic patients and normal control individuals. Norepinephrine and related compounds were measured in autistic (n = 17 unmedicated, 23 medicated; age range 9-29 years old) and normal controls (n = 27; age range 9-36 years old).
Minderaa, R.B. +4 more
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Possible Noradrenergic Dysfunction in Schizophrenia
Brain Research Bulletin, 1994In spite of extensive studies over the last 2 decades to find direct evidence in support of the dopamine hypothesis of schizophrenia, no undisputed experimental data has been obtained. In contrast, estimation of noradrenalin (another major catecholamine) and its metabolites in postmortem brain and in the cerebrospinal fluid appears to be producing ...
K, Yamamoto +4 more
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Noradrenergic mechanisms in the prefrontal cortex
Journal of Psychopharmacology, 1997There is growing evidence that noradrenergic inputs to the prefrontal cortex (PFC) play an important role in regulating its function. This paper reviews the pharmacological control of noradrenaline (NA) release in this region, with particular reference to our studies using brain microdialysis, and also describes how NA levels are modulated by ...
D J, Nutt +3 more
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