Beta‐adrenergic blockers are effective in migraine prevention but can induce neuropsychiatric side effects, including vivid dreams and nightmares. Their lipophilicity allows penetration of the central nervous system, where β1‐adrenergic blockade may disrupt REM sleep, alter noradrenergic activity, and suppress melatonin secretion, contributing to ...
Carlos R. Silva-Rosas +4 more
wiley +1 more source
Atomoxetine reverses attentional deficits produced by noradrenergic deafferentation of medial prefrontal cortex [PDF]
Lori A. Newman +2 more
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Background Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). In addition to postural instability, rigidity, tremor, and bradykinesia, patients will experience depression and/or anxiety at any time during PD.
Maryam Ezzedin +9 more
wiley +1 more source
Propofol regulates arousal by enhancing inhibitory synaptic transmission of noradrenergic neurons in the locus coeruleus of adult male mice [PDF]
Tatsuya Abe +7 more
openalex +1 more source
Epilepsy is a neurological disorder characterized by repeated, unprovoked seizures arising from abnormal electrical activity in the brain. The management of epilepsy presents several significant challenges. One of these challenges involves drug resistance, where seizures persist despite treatment with multiple antiepileptic drugs, requiring a tailored ...
Mukul Shyam +5 more
wiley +1 more source
Neural Circuit Connections and Functions of Locus Coeruleus-Norepinephrine System. [PDF]
Hao M, Li F, Duan JW, Han MH.
europepmc +1 more source
Involvement of endothelins in deoxycorticosterone acetate–salt hypertension through the modulation of noradrenergic transmission in the rat posterior hypothalamus [PDF]
Tamara Abramoff +6 more
openalex +1 more source
The Contribution of the Locus Ceruleus-Norepinephrine System to the Coupling between Pupil-Linked Arousal and Cortical State. [PDF]
Weiss E, Liu Y, Wang Q.
europepmc +1 more source
Modulation of the Neurovascular Unit by the Locus Coeruleus-Norepinephrine System: From Physiological Mechanisms to Therapeutic Applications. [PDF]
Pan Z +7 more
europepmc +1 more source
The Locus Coeruleus-Noradrenergic System in the Healthy and Diseased Brain: A Narrative Review. [PDF]
Caestecker S +5 more
europepmc +1 more source

