Results 61 to 70 of about 96,327 (352)
eLife, 2023 In a constantly changing environment, organisms must track the current relationship between actions and their specific consequences and use this information to guide decision-making.
Juan Carlos Cerpa +7 more
doaj +1 more source
Lack of kinase-independent activity of PI3Kγ in locus coeruleus induces ADHD symptoms through increased CREB signaling. [PDF]
, 2015 Although PI3Kγ has been extensively investigated in inflammatory and cardiovascular diseases, the exploration of its functions in the brain is just at dawning.
Alessandra Ghigo +10 more
core +1 more source
Noradrenergic Modulation of Fear Conditioning and Extinction
Frontiers in Behavioral Neuroscience, 2018 The locus coeruleus norepinephrine (LC-NE) system plays a broad role in learning and memory. Here we begin with an overview of the LC-NE system. We then consider how both direct and indirect manipulations of the LC-NE system affect cued and contextual ...
Thomas F. Giustino, Stephen Maren
semanticscholar +1 more source
Noradrenergic symptom cluster in depression
Neuropsychiatric Disease and Treatment, 2011 Stuart Montgomery1, Mike Briley21Imperial College School of Medicine, London, UK; 2NeuroBiz Consulting and Communication, Castres, FranceDepression is characterized by a wide range of diverse symptoms, the severity of which can be quantified by various depression rating scales, such as the Montgomery Asberg Depression Rating Scale.
Mike Briley, Stuart Montgomery
openaire +6 more sources
Strategies to Treat Chronic Pain and Strengthen Impaired Descending Noradrenergic Inhibitory System
International Journal of Molecular Sciences, 2019 Gabapentinoids (gabapentin and pregabalin) and antidepressants (tricyclic antidepressants and serotonin noradrenaline reuptake inhibitors) are often used to treat chronic pain.
Ken-ichiro Hayashida, H. Obata
semanticscholar +1 more source
Parkinson's disease dementia: a neural networks perspective. [PDF]
, 2015 In the long-term, with progression of the illness, Parkinson's disease dementia affects up to 90% of patients with Parkinson's disease. With increasing life expectancy in western countries, Parkinson's disease dementia is set to become even more ...
Foltynie, T, Gratwicke, J, Jahanshahi, M
core +1 more source
The central noradrenergic system: an overview
African Journal of Psychiatry, 2007 The central noradrenergic system belongs to a group of brainstem neuromodulatory systems previously referred to as the ascending reticular activating system. In this article a heuristic model is presented of the central noradrenergic system depicting the major projections to other cerebral areas, its interactions with other neuromodulatory systems ...
Viljoen, Margaretha, Panzer, Annie
openaire +5 more sources
Biomolecules, 2020 Noncompetitive N-methyl-D-aspartate/glutamate receptor (NMDAR) antagonists contribute to the pathophysiology of schizophrenia and mood disorders but improve monoaminergic antidepressant-resistant mood disorder and suicidal ideation. The mechanisms of the
Motohiro Okada, Kouji Fukuyama
doaj +1 more source
Frontiers in Cellular Neuroscience, 2022 Processing of contextual information during a new episodic event is crucial for learning and memory. Neuromodulation in the hippocampus and prefrontal cortex plays an important role in the formation of associations between environmental cues and an ...
Theodoros Tsetsenis +3 more
doaj +1 more source
Magnetic resonance imaging of noradrenergic neurons
Brain Structure and Function, 2019 Noradrenaline is a neurotransmitter involved in general arousal, selective attention, memory, inflammation, and neurodegeneration. The purpose of this work was to delineate noradrenergic neurons in vivo by T1-weighted MRI with magnetization transfer (MT).
Takashi Watanabe +4 more
semanticscholar +1 more source