Results 41 to 50 of about 10,132 (232)

Interaction between Mesocortical and Mesothalamic Catecholaminergic Transmissions Associated with NMDA Receptor in the Locus Coeruleus

Biomolecules, 2020
Noncompetitive N-methyl-D-aspartate/glutamate receptor (NMDAR) antagonists contribute to the pathophysiology of schizophrenia and mood disorders but improve monoaminergic antidepressant-resistant mood disorder and suicidal ideation. The mechanisms of the
Motohiro Okada, Kouji Fukuyama
doaj   +1 more source

Cellular composition and circuit organization of the locus coeruleus of adult mice

eLife, 2023
The locus coeruleus (LC) houses the vast majority of noradrenergic neurons in the brain and regulates many fundamental functions, including fight and flight response, attention control, and sleep/wake cycles.
Andrew McKinney, Ming Hu, Amber Hoskins, Arian Mohammadyar, Nabeeha Naeem, Junzhan Jing, Saumil S Patel, Bhavin R Sheth, Xiaolong Jiang   +8 more
doaj   +1 more source

Noradrenergic vasoconstriction of pig prostatic small arteries

, 2008
The current study investigated the distribution of adrenergic nerves and the action induced by noradrenaline (NA) in pig prostatic small arteries. Noradrenergic innervation was visualized using an antibody against dopamine-beta-hydroxylase (DBH), and the
Bustamante Alarma, Salvador, Martínez Sainz, María Del Pilar, Hernández Rodríguez, Medardo Vicente, Orensanz Muñoz, Luis Miguel, Navarro Dorado, Jorge, García Sacristán, Albino, Recio Visedo, María Paz, Prieto Ocejo, Dolores   +7 more
core   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Noradrenergic Locus Coeruleus pathways in pain modulation.

, 2016
The noradrenergic system is crucial for several activities in the body, including the modulation of pain. As the major producer of noradrenaline (NA) in the central nervous system (CNS), the Locus Coeruleus (LC) is a nucleus that has been studied in ...
Llorca-Torralba, Meritxell, Borges, Gisela, Neto, Fani, Mico, Juan Antonio, Neto, Fani L., Berrocoso, Esther, Micó Segura, Juan Antonio, Berrocoso Domínguez, Esther María, Llorca Torralba, Meritxell   +8 more
core   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Activation of a Locus Coeruleus to Dorsal Hippocampus Noradrenergic Circuit Facilitates Associative Learning

Frontiers in Cellular Neuroscience, 2022
Processing of contextual information during a new episodic event is crucial for learning and memory. Neuromodulation in the hippocampus and prefrontal cortex plays an important role in the formation of associations between environmental cues and an ...
Theodoros Tsetsenis, Julia K. Badyna, Rebecca Li, John A. Dani   +3 more
doaj   +1 more source

The Role of Noradrenergic and Glutamatergic Signaling in Noradrenergic Neurons in Respiratory Control

The FASEB Journal, 2021
Central noradrenergic (NA) neurons are a critical component of the brainstem respiratory network that maintains blood CO 2 and O 2 levels through respiratory chemoreflexes.
Yuan Chang, Jenny Sun, Andrew McKinney, Xiaolong Jiang, Russell Ray   +4 more
openaire   +1 more source

Revisitando os mecanismos de modulação noradrenérgica sobre as memórias de medo: do fisiológico ao disfuncional [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2015.O sistema noradrenérgico é implicado tradicionalmente no processamento das memórias emocionais por meio
Gazarini, Lucas
core  

Noradrenergic modulation of cognition: Therapeutic implications

, 2013
The noradrenaline (norepinephrine) system exerts profound influences on cognition via ascending projections to the forebrain, mostly originating from the locus coeruleus.
Robbins, Trevor W., Chamberlain, Samuel R.   +1 more
core   +1 more source